Abstract
Immunomodulation is a process, which alters the immune system of an organism by interfering with its functions. This interference results in either immunostimulation or immunosuppression. An immunomodulator is any substance that helps to regulate the immune system. This "regulation" is a normalization process, so that an immunomodulator helps to optimise immune response. Immunomodulators are becoming very popular in the worldwide natural health industry as these do not tend to boost immunity, but to normalize it. Keeping this in view, major efforts have to be directed to modulate the immune responses, to permit effective treatment of various ailments associated with immune system and thus the development of a safe and effective immunomodulator for clinical us. Leaves of Stevia rebaudiana are a source of several sweet glycosides of steviol. The major glycoside, stevioside, diterpenoid glycoside--is used in oriental countries as a food sweetener. Its medical use is also reported as a heart tonic. Besides, it is used against obesity, hypertension, and stomach burn and to lower uric acid levels. Here in this study, stevioside was tested for its immunomodulatory activity on different parameters of the immune system at three differen...Continue Reading
References
Dec 16, 1983·Journal of Immunological Methods·T Mosmann
Dec 1, 1982·Cellular Immunology·L W PoulterG Panayi
May 1, 1981·Agents and Actions·N S Doherty
Nov 7, 1998·Life Sciences·P ChanJ T Cheng
May 15, 2007·Vaccine·Anamika KhajuriaG N Qazi
Citations
Jun 19, 2014·Nutrition Journal·Ian A Myles
Jul 1, 2014·International Immunopharmacology·Tiancheng WangNaisheng Zhang
Dec 30, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria Fabrizio FerrazzanoAntonino Pollio
Nov 13, 2008·Pharmacology & Therapeutics·Varanuj Chatsudthipong, Chatchai Muanprasat
Jul 5, 2011·Journal of Animal Physiology and Animal Nutrition·M DaneshyarN Everaert
Dec 3, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Jonathan D UrbanSteve L Taylor
Feb 16, 2013·Food Chemistry·Sha LiYongmei Xia
Oct 12, 2014·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Jing BaChunhong Wang
Aug 21, 2014·Vaccine·Carolien E van de SandtGuus F Rimmelzwaan
Jul 12, 2018·Current Nutrition Reports·Edward RojasIsaac Kuzmar
May 9, 2019·International Journal of Food Sciences and Nutrition·Hanna Bessler, Meir Djaldetti
May 27, 2014·Inflammation·Tiancheng WangNaisheng Zhang
Oct 28, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Marcela Sánchez-DelgadoIrazú Contreras
Jun 5, 2020·Critical Reviews in Food Science and Nutrition·Roberto Castro-MuñozEmilia Gontarek
Aug 25, 2018·Journal of Dairy Science·H R McCainM A Drake
Aug 20, 2019·Phytotherapy Research : PTR·Bahare SalehiNatália Martins
Jul 13, 2013·Food & Function·Lv YingjianLi Zhi
Oct 24, 2018·Veterinary Research·Stina HellmanCaroline Fossum
Mar 2, 2019·Proceedings of the National Academy of Sciences of the United States of America·Xiao-Cui LuoLiquan Huang
Jul 24, 2018·Chinese Medicine·Aleksandra TarasiukJakub Fichna
Jun 2, 2018·BioMed Research International·Cristian Angel Rosales-GómezJorge Alberto Escoto-Herrera
Aug 9, 2020·Frontiers in Endocrinology·Eleonora MoriconiMassimiliano Caprio
Mar 9, 2018·Frontiers in Pharmacology·Md Shafiullah ShajibMohammad A Rashid
Sep 20, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Latha SRay R S
Aug 1, 2020·Poultry Science·Jingle JiangFangxiong Shi
Aug 2, 2011·Journal of Agricultural and Food Chemistry·Yongfeng LiuHelin Ye