PMID: 8596991Oct 1, 1995Paper

Immunisation against hepatitis B viral infection--a study of South African anaesthesiologists

South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
R E HodgsonA Smith

Abstract

The practice of anaesthesia involves exposure to blood or bloodstained secretions which may be contaminated with transmissible pathogens including the hepatitis B virus (HBV). This study was undertaken to assess the impact of freely available hepatitis B vaccine and applications of universal precautions against blood exposure on the uptake of immunisation and prevalence of HBV markers in South Africa anaesthesiologists. Anaesthesiologists from the Department of Anaesthesia of the University of Natal and those attending a continuing medical education course in Cape Town in March 1993 participated in the study. Each participant completed a questionnaire giving details of previous exposure to HBV, immunisation status and details of immunisation. Blood samples were obtained on a voluntary basis for determination of HBV serology. One hundred and twenty-one anaesthesiologists participated in the study; 36 were unimmunised, of whom 18 (50%) were seropositive for HBV markers. More experienced anaesthesiologists (> 10 years) tended both not to be immunised and to be seropositive, indicating previous exposure to HBV. Eighty-five participants were immunised. Intradermal immunisation caused significantly less seroconversion than the intram...Continue Reading

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