Immunity and autoimmunity induced by polyomaviruses: clinical, experimental and theoretical aspects

Advances in Experimental Medicine and Biology
O P RekvigUgo Moens

Abstract

In this chapter, polyomaviruses will be presented in an immunological context. Principal observations will be discussed to elucidate humoral and cellular immune responses to different species of the polyomaviruses and to individual viral structural and regulatory proteins. The role of immune responses towards the viruses or their proteins in context of protection against polyomavirus induced tumors will be described. One central aspect of this presentation is the ability of polyomaviruses, and particularly large T-antigen, to terminate immunological tolerance to nucleosomes, DNA and histones. Thus, in the present chapter we will focus on clinical, experimental and theoretical aspects of the immunity to polyomaviruses.

Citations

May 6, 2011·Arthritis Research & Therapy·Annica HedbergOle Petter Rekvig
Apr 11, 2012·Clinical & Developmental Immunology·Serena DelbuePasquale Ferrante
Apr 25, 2014·Journal of Virology·Stian HenriksenChristine Hanssen Rinaldo
May 29, 2010·International Immunology·Svetlana V BaranovaGeorgy A Nevinsky
Aug 28, 2013·The Journal of Biological Chemistry·Clinton D OrebaughFred W Perrino
May 8, 2013·Reviews in Medical Virology·Ugo MoensBernhard Ehlers
Jan 18, 2012·Nature Reviews. Nephrology·Adriana Migliorini, Hans-Joachim Anders
Jun 3, 2015·Nature Reviews. Rheumatology·Ole P Rekvig
Mar 17, 2018·Frontiers in Immunology·Ole Petter Rekvig
Jan 29, 2014·Arthritis & Rheumatology·Ole Petter RekvigNatalya Seredkina
Dec 7, 2010·Neurobiology of Disease·Carla LintasAntonio M Persico

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