PMID: 8940963Nov 1, 1996Paper

Immunity and morbidity in Schistosoma mansoni infection: quantitative aspects

The American Journal of Tropical Medicine and Hygiene
A E ButterworthR F Sturrock

Abstract

Immunity to Schistosoma mansoni infection in humans can be studied most easily by monitoring serially the intensity of reinfection that occurs among individuals who have undergone chemotherapeutic cure, and whose levels of exposure to contaminated water is subsequently observed. Parallel studies can then be made of those immune responses that are correlated with an observed resistance to reinfection. This paper describes some of the difficulties associated with this approach, with particular reference to the authors' own studies in Kenya, and highlights a possible role of immunoglobulin E antibodies against adult worm antigens in mediating immunity.

Citations

Mar 17, 2001·Tropical Medicine & International Health : TM & IH·J BethonyA Gazzinelli
Jul 27, 2001·Current Gastroenterology Reports·T W Schafer, B R Hale
Sep 14, 2001·Tropical Medicine & International Health : TM & IH·P BoisierV E Ravaoalimalala
Jan 26, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A A CruzP J Cooper
Nov 26, 2003·Antimicrobial Agents and Chemotherapy·Sanaa BotrosAntonín Holý
Apr 3, 2004·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Manoel MedeirosEdgar M Carvalho
Sep 15, 2000·Infectious Disease Clinics of North America·I BicaM J Stadecker

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