PMID: 6976140Nov 1, 1981Paper

Immunity in migraine: the effect of heparin

Annals of Allergy
E Thonnard-Neumann, L M Neckers

Abstract

There is evidence that migraine has an immunologic component. Migraine patients have reduced levels of circulating basophils and T-lymphocytes and there is a negative correlation of T-cell levels and disease activity. Clinical improvement of migraine is observed after the repeated inhalation of heparin in those patients in whom heparin raises both basophil and T-lymphocyte values to the normal range.

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