Immunization of cattle against Theileria parva bovis and their exposure to natural challenge

Veterinary Parasitology
H T KochR A Norval

Abstract

Theileria parva bovis isolates were tested for their immunizing capacity under natural field challenge on Willsbridge Farm in the highveld of Zimbabwe. Fifteen susceptible Sussex yearlings were immunized with the Boleni stock and 15 with a mixture of three isolates from the farm, using tick-derived sporozoite stabilates. No chemoprophylaxis was used. A dose of 0.1 ml of stabilate appeared to be safe in preliminary laboratory experiments, but the reactions were severe in the Sussex cattle and one died despite treatment. Twenty-nine immunized animals and 10 controls first experienced a mild infection, starting about 15 days after their arrival at the farm. Ten of the immunized animals and four controls had schizonts in peripheral lymph nodes for variable periods; one third of those had pyrexia. Nymphal Rhipicephalus appendiculatus ticks applied to three of the reacting immunized calves transmitted Theileria taurotragi to two animals and T. parva to a third. A second Theileria infection, due to T. parva bovis, was detected shortly after the first one. Schizonts were detected in seven out of 10 controls. Pyrexia was more severe and prolonged. Two of the controls died of theileriosis. At the same time schizonts were seen in three im...Continue Reading

References

Feb 1, 1990·Molecular and Biochemical Parasitology·K P IamsA J Musoke
Nov 1, 1990·Veterinary Parasitology·H T KochA D Irvin
Jul 1, 1986·The Veterinary Quarterly·F JongejanG Uilenberg
Apr 1, 1988·Veterinary Parasitology·H T KochA D Irvin
Feb 1, 1985·Tropical Animal Health and Production·R A NorvalA F Brown
Sep 1, 1973·International Journal for Parasitology·M P CunninghamR E Purnell
Aug 1, 1982·Tropical Animal Health and Production·G UilenbergA A Spanjer
Feb 1, 1981·Tropical Animal Health and Production·N J Short, R A Norval
Jul 26, 1980·The Veterinary Record·J A LawrenceR A Norval
Nov 1, 1985·Parasitology Today·A D Irvin

❮ Previous
Next ❯

Citations

Jun 12, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·Nicola E CollinsBasil A Allsopp
Oct 30, 1999·Tropical Medicine & International Health : TM & IH·G Uilenberg
Jun 1, 1993·The Veterinary Quarterly·G UilenbergH T Koch
Dec 27, 2008·Molecular and Biochemical Parasitology·Audrey O T Lau
Nov 1, 1995·Tropical Animal Health and Production·T HoveR Mwangondwe
Aug 30, 2008·Substance Use & Misuse·Anna KokkeviPatrick Miller

❮ Previous
Next ❯

Related Concepts

Related Feeds