Immunization of normal mouse spleen cell suspensions in vitro
Dissociated cells from the spleens of unimmunized mice were cultured with and without various mammalian erythrocytes. Spleen cell suspensions cultured with heterologous red cells developed levels of hemolytic plaque-forming cells only one log(2) less than those seen in vivo. The reaction is specific for the in vitro immunizing erythrocytes. Antibody was demonstrated in the culture fluids.
Rate of hemoglobin synthesis controlled at the translational level in differentiating erythroid cells from adult mice
Restoration of the in vitro antibody response of cortisone-treated spleen cells by T cells or soluble factors
Induction of clonally restricted thymus-dependent antibody responses in vitro using phosphorylcholine derivatized sheep erythrocytes
Control of lymphocyte stimulation in vitro: "help' and "suppression' in the light of lymphoid population dynamics
Microsystem for in vitro primary and secondary immunization of channel catfish (Ictalurus punctatus) leukocytes with hapten-carrier conjugates
A new cell culture method (the lateral diffusion system) suitable for the induction of antibody-forming cells in vitro
The elimination of graft-versus-host cells from an immune population. A potential tool in cancer immunotherapy
Effects of phosphorylcholine-lipopolysaccharide conjugates on the induction of anti-idiotype-mediated B-cell tolerance
Immunomodulating activities of ethylene-2,2'-bis(dithio)bis(ethanol) and related compounds. Effects on murine lymphocyte proliferation and functions in vitro
Differential in vitro effects of physiological and atmospheric oxygen tension on normal human peripheral blood mononuclear cell proliferation, cytokine and immunoglobulin production
Blocking of primary in vitro antibody responses to thymus-independent and thymus-dependent antigens with antiserum specific for IgM or IgD
Differentiation of antibody-forming cells in toad spleen. A study using density and sedimentation velocity cell separation
In vitro and in vivo studies of the immune response to sheep erythrocytes using partially purified cell preparations
The enhancing effect of bone marrow cells on the primary immune response of the isolated perfused spleen
In vitro stimulation of antibody formation by peritoneal cells. I. Plaque technique of high sensitivity enabling access to the cells
Carrier function in anti-hapten antibody responses. IV. Experimental conditions for the induction of hapten-specific tolerance or for the stimulation of anti-hapten anamnestic responses by "nonimmunogenic" hapten-polypeptide conjugates
Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes
The allogeneic effect in inbred mice. 3. Unique antigenic structural requirements in the expression of the phenomenon on unprimed cell populations in vivo
Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates
Generation of cytotoxic lymphocytes in mixed lymphocyte reactions. I. Specificity of the effector cells
Activation of T and B lymphocytes in vitro. II. Biological and biochemical properties of an allogeneic effect factor (AEF) active in triggering specific B lymphocytes
Collaboration of allogeneic T and B lymphocytes in the primary antibody response to sheep erythrocytes in vitro
Experimental amyloidosis: the inducer is a polyclonal B-cell activator to which susceptibility is under genetic control
Sheep red blood cell-specific helper activity in rat thoracic duct lymphocyte populations positively selected for reactivity to specific strong histocompatibility alloantigens
Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen
B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus-dependent and independent forms of the same hapten
B-cell tolerance. III. Effect of papain-mediated cleavage of cell surface IgD on tolerance susceptibility of murine B cells
A dichotomy between the expression of IgD on B cells and its requirement for triggering such cells with two T-independent antigens
Mechanisms of idiotype suppression. I. In vitro generation of idiotype-specific suppressor T cells by anti-idiotype antibodies and specific antigen
Mechanisms of idiotype suppression. IV. Functional neutralization in mixtures of idiotype-specific suppressor and hapten-specific suppressor T cells
In vitro generation of antigen-specific hemolytic plaque-forming cells from human peripheral blood mononuclear cells
Quantitative studies on T cell diversity. III. Limiting dilution analysis of precursor cells for T helper cells reactive to xenogeneic erythrocytes
Mouse spleen cells cultivated in homologous serum can make primary antibodies in vitro provided the T-cells are non-specifically activated
When allogeneic mouse spleen cells are mixed in vitro the T-cells secrete a product which guides the maturation of B-cells
Unmasking and functional characterization of T-cell-replacing factors obtained from supernatants of allogeneic spleen cell mixtures
Lymphocyte-mediated cytotoxicity against tumor cells specificity and characterization of concanavalin A-activated cytotoxic effector lymphocytes
In vitro immune response of primed mouse spleen cells as affected by the time of antigenic stimulation
Anti-phenyltrimethylamino immunity in mice. II. L-Tyrosine-p-azophenyltrimethylammonium-induced suppressor T cells selectively inhibit the expression of B-cell clones bearing a cross-reactive idiotype
Immunogenicity of macrophage-bound antigens: the requirement for hapten and carrier determinants to be on the same molecule for T and B lymphocyte collaboration
In vitro humoral immune response of human peripheral blood lymphocytes to tetanus toxoid sepharose 4B
Cooperation of dendritic cells with naïve lymphocyte populations to induce the generation of antigen-specific antibodies in vitro
In vitro evaluations of innate and acquired immune responses to electrospun polydioxanone-elastin blends
Functional assays are mandatory for a correct prediction of immunotoxic properties of compounds in vitro
Cellular immunity to heterologous erythrocytes in vitro. I. The role of surface-adherent cells and specific mediators in an effector mechanism
Modulation of murine innate and acquired immune responses following in vitro exposure to electrospun blends of collagen and polydioxanone
In vitro studies of "antigenic competition". I. The comparative responses of normal and "immune" lymphoid cell populations
Ia-restricted interaction between normal lymphoid cells and SJL lymphoma (RCS) leading to lymphokine production. I. Enhancement and suppression of antibody formation to TI antigens by supernatants and cells from cocultures of RCS and lymphoid cells
Biological characterization of T and B lymphocytes separated from normal mouse spleen by a physical adherence column method
Immune response to phosphorylcholine II, natural "auto"-anti-receptor antibody in neonatal Balb/c mice
Cells involved in cell-mediated and transplantation immunity. 3. The organ source(s) of the cells in the normal rabbit which mediate a reaction of cellular immunity in vitro
Defective B-cell tolerance in New Zealand black mice. Fc receptor-independence of resistance to low-epitope-density tolerogens
Evaluation of murine splenic cell type metabolism of benzo[a]pyrene and functionality in vitro following repeated in vivo exposure to benzo[a]pyrene
Characteristics of efferent lymphatic cells from the regional lymph nodes in rabbits sensitized with SRBC
Minimal requirements for in vitro activity of chemically defined synthetic antigens as immunogenic carrier molecules
Tolerance rendered by neonatal treatment with anti-idiotypic antibodies: induction and maintenance in athymic mice
Characterization and function of autoreactive T-lymphocyte clones isolated from normal, unprimed mice
Reversal of Con A-induced suppression by a platelet-derived factor which binds to activated suppressor T cells
The lack of compensatory increases of cells producing anti-phosphorylcholine antibodies bearing other idiotypes in TEPC-15 idiotype-suppressed inbred and outbred mice
The effect of second signals on the induction of B cell tolerance: failure of helper T cells to block tolerance induction
Immune response of guinea pig lymphoid cells in vitro. III. Induction by concanavalin A of a secondary anti-TNP response in primed guinea pig cells
Specific antibody responses of primary cells from different cell sources are able to predict immunotoxicity in vitro
Using immunotoxicity information to improve cancer risk assessment for polycyclic aromatic hydrocarbon mixtures
Detection of single antibody-secreting cells generated after in vitro antigen-induced stimulation of human peripheral blood lymphocytes
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Alzheimer's Disease: MS4A
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Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
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Genetic Screens in iPSC-derived Brain Cells
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This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Pharmacology of Proteinopathies
This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.
Alignment-free Sequence Analysis Tools
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