PMID: 7032199Jul 1, 1981Paper

Immuno-cyto-chemical staining of mid-gut carcinoid tumours with sequence-specific gastrin antisera

Acta Pathologica Et Microbiologica Scandinavica. Section A, Pathology
E Wilander, M El-Salhy

Abstract

Twenty typical mid-gut carcinoid tumours were examined for the presence of gastrin immuno-reactivity to antisera specific to the C-terminal pentapeptide or to the mid-portion of gastrin-17. Pentagastrin immuno-reactivity was found in seven cases, and in one of these reactivity to antiserum against the mid-portion of gastrin-17 was also observed. The results are in accordance with the previous observation that argyrophil tumour cells are present in mid-gut carcinoid tumours and may explain why peptic ulcer disease is sometimes seen in association with the carcinoid syndrome.

References

Dec 1, 1977·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L I Larsson, J F Rehfeld

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