Immunoassay in healthcare testing applications

Journal of Opioid Management
Anne Z DePriestTimothy A Robert

Abstract

Immunoassay is used extensively for drug testing in pain management. Drug testing for the purpose of compliance monitoring is fundamentally different from forensic applications, which may rely on immunoassay screening to rapidly identify "negative" samples. In clinical settings, focus is shifted from identification of select drugs of abuse with low positivity rates to detection of a wide variety of licit and illicit compounds with expected high positivity rates. The primary drug classes of interest in this population, opioids and benzodiazepines, require special testing considerations when immunoassay is used. This review highlights the performance characteristics of immunoassay, with special emphasis on prescription drug classes and testing at the point-of-care.

Citations

Dec 4, 2015·Current Opinion in HIV and AIDS·Frances M Cowan, Sinead Delany-Moretlwe
Aug 24, 2016·Journal of Analytical Toxicology·Roger L BertholfGary M Reisfield
Dec 1, 2017·Anesthesia and Analgesia·Gagan Mahajan
Dec 6, 2017·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Charles E ArgoffLynn R Webster
Feb 23, 2019·Critical Reviews in Toxicology·Andrea G BarthwellKenneth Egli
Oct 11, 2017·Critical Reviews in Clinical Laboratory Sciences·Tai C KwongChristine Moore
Feb 1, 2020·International Anesthesiology Clinics·A Zara HerskovitsLynne Uhl
Oct 21, 2016·Journal of the International AIDS Society·Frances M CowanLinda-Gail Bekker
May 31, 2017·Journal of Addiction Medicine

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