PMID: 6971015Sep 1, 1980Paper

Immunochemical characteristics of human anti-T antibodies

Vox Sanguinis
Y D Kim

Abstract

A specific and sensitive radioimmunoassay was developed to investigate the immunochemical properties of serum anti-T antibodies. Evidence was presented that the radioimmunoassay can measure non-agglutinating as well as agglutinating anti-T antibodies, while the hemagglutination method can detect only the latter type. Although the hemagglutination method failed to detect anti-T agglutinins in cord sera, the radioimmunoassay results demonstrated the presence of non-agglutinating antibodies. Presence of 1% polyethylene glycol potentiated some of the originally nonagglutinating antibodies to produce a hemagglutination reaction. Immunochemical characteristics associated with the human anti-T antibodies are discussed.

References

Jan 1, 1979·Immunological Communications·Y D KimM Hargie
Mar 1, 1975·Carbohydrate Research·G F Springer, P R Desai
Jun 1, 1975·Die Naturwissenschaften·G F Springer, P R Desai
Feb 26, 1974·Biochemistry·G S David, R A Reisfeld
Jul 1, 1969·The Journal of Clinical Investigation·G F Springer, R E Horton
Feb 1, 1958·Proceedings of the National Academy of Sciences of the United States of America·G F Springer, N J Ansell
Sep 1, 1947·The Australian Journal of Experimental Biology and Medical Science·F M BURNET, S G ANDERSON
Sep 1, 1947·The Australian Journal of Experimental Biology and Medical Science·P E LIND, N R McARTHUR

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