Immunochemical localization of the small leucine-rich proteoglycan lumican in human predentine and dentine

Archives of Oral Biology
R C HallD Lloyd

Abstract

The immunocalization of the small interstitial leucine-rich keratan sulphate proteoglycan lumican was studied in human teeth using a polyclonal antibody towards lumican and a standard indirect peroxidase technique. There was intense labelling for lumican in predentine, with immunopositivity also observed in and around the tubules, around the odontoblasts and in the pulp with a fibrillar distribution. The previous reported ability of lumican to control collagen fibrillogenesis and it putative function in collagen spacing suggest potential roles for lumican in predentine in relation to mineralization.

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Citations

Nov 19, 2004·Calcified Tissue International·Anna M MilanRachel J Waddington
Jun 21, 2005·Journal of Structural Biology·Sunita P HoGrayson W Marshall
Jun 5, 2003·Medical Hypotheses·Y-N Wang, J E Sanders
Sep 30, 2004·Anatomical Science International·Mitsuko MoriguchiTakaaki Yanagisawa
May 10, 2002·Journal of Biomedical Materials Research·L BreschiJ Perdigão
Mar 22, 2003·European Journal of Oral Sciences·Ulrika PeterssonMikael Wendel
Feb 8, 2006·European Journal of Oral Sciences·Rachael V SugarsMikael Wendel
Apr 20, 2005·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·A K S ArambawattaM Wakita
Oct 28, 2014·Journal of Periodontology·Won Hee LimJill A Helms
Oct 6, 2015·Australian Dental Journal·K StankoskaL E Bertassoni
Oct 18, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G EmberyM Goldberg
Dec 29, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Annalisa MazzoniLorenzo Breschi
Nov 15, 2008·The Journal of Biological Chemistry·Sebastian Kalamajski, Åke Oldberg
Sep 16, 2019·Carbohydrate Polymers·Eduardo ListikAna Carla Raphaelli Nahás-Scocate

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