PMID: 2489912Nov 1, 1989Paper

Immunochemical properties of dental plaque proteins. 1. Immunochemical similarity between proteins of human dental plaque, serum and saliva

Stomatolos̆ki glasnik Srbije
G Stefanović, N Milosević-Jovcić

Abstract

The significance of human dental plaque proteins that are of endogenous origin, probably serum or saliva, is still not clear. Little is known about the physico-chemical and immunochemical properties of plaque proteins. This information, however, might be of significance for a better understanding of the possible role of plaque proteins in the aethiology of some oral diseases. The purpose of this work was to identify several proteins in dental plaque of healthy people as well as to investigate the immunochemical similarity of these proteins with appropriate serum or saliva proteins. The results showed that with the exception of IgG all the other proteins detected in plaque were immunochemically identical with the appropriate serum or saliva proteins. The presence of IgG in plaque revealed immunochemical dissimilarity with partial identity with serum IgG. It was established that IgG plaque had no Fc portion. The results were discussed from the current point of view to the problem of immunochemical similarity between proteins in general, as well as from the aspect of specificity of used antisera.

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