Immunochemical properties of Vi antigen from Salmonella typhi Ty2: presence of two antigenic determinants.

Infection and Immunity
B Szewczyk, A Taylor

Abstract

Antigen Vi of Salmonella typhi was found to have at least two antigenic determinants. In one of them, O-acetyl moiety played a dominant role. The second antigenic determinant did not involve O-acetyl residues, but both carboxyl and N-acetyl groups were necessary for the antigen-antibody reaction. These results were obtained by performing serological tests with antigen Vi, with its structural analog, polygalacturonic acid, and with the derivatives of both polysaccharides.

References

Dec 1, 1975·The Journal of General Virology·B KwiatkowskiS Stirm
Jul 1, 1967·European Journal of Biochemistry·D HungererI Orskov
Oct 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·M E WEBSTERM E FREEMAN
Sep 1, 1956·Bacteriological Reviews·E NETER
Jul 1, 1959·Biochimica Et Biophysica Acta·F SNYDER, N STEPHENS

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