Abstract
The present immunocytochemical study examines in the rat ovary the pattern of expression of connexin 43 (Cx43), a subunit of gap junctions. Using a well-characterized specific antiserum against rat Cx43, immunoreactivity was not detected in the fetal ovary, i.e., prior to follicular formation. However, in the ovary of 20-day-old, 35-day-old, and adult rats, strong Cx43-immunoreactivity was associated with the cell borders of the follicular epithelium/granulosa cells of all developmental stages (primordial follicles, preantral and antral secondary follicles). In general, immunoreactivity of the granulosa cells of large antral follicles appeared more intense than the one of smaller follicles. Staining was also seen in oocytes (cytoplasmic staining). Theca cells of large antral follicles, but not of small follicles were immunoreactive. Immunoreactive interstitial cells were not seen in ovaries of 20- and 35-day-old animals, but staining in these cells was present in adult rats. In large follicles with signs of atresia, granulosa cells lacked Cx43-immunoreactivity, whereas Cx43-immunoreactivity in their theca interna strikingly increased. Corpora lutea in the cyclic adult rats were heterogeneously stained, with either no detectable...Continue Reading
References
Feb 1, 1975·The Anatomical Record·D F Albertini, E Anderson
Dec 1, 1992·Mutation Research·T M Crisp
Aug 1, 1992·American Journal of Obstetrics and Gynecology·T TabbR Garfield
Aug 1, 1992·Molecular Biology of the Cell·P P MehtaB Rose
Nov 1, 1992·American Journal of Obstetrics and Gynecology·N SakaiR E Garfield
Jul 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R RajahA N Hirshfield
Aug 1, 1992·Experimental Cell Research·A MayerhoferM Gratzl
Feb 1, 1990·The Journal of Cell Biology·B RisekN B Gilula
Jan 1, 1991·The Biochemical Journal·D W LairdJ P Revel
Mar 1, 1991·Neuron·M V BennettJ C Sáez
Aug 1, 1991·Endocrinology·A MayerhoferM Gratzl
Aug 1, 1991·Endocrinology·A MayerhoferM Gratzl
Nov 1, 1991·Endocrinology·D A RedmerL P Reynolds
Jan 1, 1991·International Review of Cytology·A N Hirshfield
Jun 1, 1990·The Journal of Membrane Biology·L S MusilD A Goodenough
Jan 1, 1990·Molecular Carcinogenesis·M RogersJ S Bertram
Feb 1, 1989·The Journal of Cell Biology·E C BeyerD A Goodenough
Aug 1, 1987·Endocrine Reviews·A Amsterdam, S Rotmensch
Dec 1, 1987·The Journal of Cell Biology·E C BeyerD A Goodenough
Apr 1, 1988·The Journal of Cell Biology·R W KeaneU Rutishauser
Jul 1, 1987·Developmental Biology·W J LarsenG D Brunner
Jan 1, 1985·Endocrine Reviews·G F EricksonC Hofeditz
Jan 1, 1973·The Anatomical Record·F B MerkC R Botticelli
Apr 1, 1972·Endocrinology·F B MerkJ T Albright
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
May 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·A AmsterdamK J Catt
Nov 1, 1982·Developmental Biology·R C Burghardt, R L Matheson
Nov 1, 1982·Biology of Reproduction·C P Puri, R E Garfield
Jan 1, 1981·Cell and Tissue Research·R C Burghardt, E Anderson
Sep 24, 1993·Cell·L S Musil, D A Goodenough
Jun 13, 1994·FEBS Letters·A MayerhoferM Gratzl
Feb 1, 1994·Biology of Reproduction·J F Wiesen, A R Midgley
Jun 1, 1993·Endocrinology·S J LyeT Petrocelli
Sep 1, 1993·Molecular Reproduction and Development·G ValdimarssonG M Kidder
Citations
Jul 1, 1997·Molecular Reproduction and Development·I Granot, N Dekel
Aug 24, 2000·Molecular Reproduction and Development·F NuttinckJ E Fléchon
Oct 1, 1996·Endocrine·A T Grazul-BilskaL P Reynolds
Dec 12, 2003·Fertility and Sterility·Meng-Yin TsaiShiuh-Young Chang
Apr 20, 2005·Molecular and Cellular Endocrinology·Stefan Cuoni Teilmann
Oct 1, 1996·Prostaglandins·A T Grazul-BilskaD A Redmer
Feb 5, 2003·Biology of the Cell·Véronique Serre-BeinierPaolo Meda
Nov 1, 1996·Zygote : the Biology of Gametes and Early Embryos·G A DissenS R Ojeda
Jul 22, 2005·The Journal of Reproduction and Development·Jun Babaan FeranilToshihiko Nakao
Jul 19, 2013·PloS One·Nicolas SantiquetFrançois J Richard
Feb 8, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·Disha PantAnna T Grazul-Bilska
Jan 15, 2014·Molecular Human Reproduction·Hsun-Ming ChangPeter C K Leung
Feb 16, 2016·Theriogenology·Andréa Moreira Sampaio da SilvaAna Paula Ribeiro Rodrigues
Apr 15, 2006·Cell Communication & Adhesion·Alexander M SimonCharity L Jackson
Mar 12, 2003·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·E Martha Pérez-ArmendarizIrma Villalpando
May 14, 2014·Journal of Cellular Biochemistry·Tanya Zappitelli, Jane E Aubin
Dec 20, 2005·Biochimica Et Biophysica Acta·Laetitia MichonPaolo Meda
Oct 18, 2011·Biochimica Et Biophysica Acta·Ilaria PotolicchioPaolo Meda
Jul 11, 2006·Gene Expression Patterns : GEP·Lauri A Willingham-RockyRobert C Burghardt
Nov 25, 2000·Biology of Reproduction·B SommersbergA Mayerhofer
May 30, 2003·Biology of Reproduction·Réjane MarchalGhylène Goudet
Mar 1, 2002·Biology of Reproduction·Irit GranotNava Dekel
Jun 25, 2002·Biology of Reproduction·Digbo BolambaVaughan H Lee
Oct 21, 2016·Polish Journal of Veterinary Sciences·A J KorzekwaA A Szczepańska
Oct 29, 2015·Journal of Molecular Endocrinology·Wei-Ling FangJiuan-Jiuan Hwang
Apr 20, 1999·Biology of Reproduction·S C JunejaG M Kidder
Oct 21, 2011·Physiological Reviews·Domenico BoscoPaolo Meda
Jul 14, 2000·Molecular Endocrinology·A BullingA Mayerhofer
Sep 25, 2003·Physiological Reviews·Juan C SaezEric C Beyer
Jan 10, 2013·American Journal of Physiology. Endocrinology and Metabolism·Huatao ChenMasa-aki Hattori
Jul 31, 2021·Gene Expression Patterns : GEP·S KumarM S Chauhan