Immunocytochemical demonstration of beta 1-subunit of Na+/K(+)-ATPase in the mechanoreceptive Ruffini-like endings of the rat incisor ligament

Archives of Oral Biology
K OchiT Maeda

Abstract

The localization of one of the isoforms of Na+/K(+)-ATPase, the beta 1-subunit, was investigated in the periodontal Ruffini endings of rat incisors by light- and electron-microscopic immunocytochemistry. Immunoreactivity for the rat beta 1-subunit followed the pattern of dendritic terminal arborization in the alveolar half of the lingual periodontal ligament. Ultrastructurally, the reaction products were localized in dilatations of axons, possibly the terminals of Ruffini-like endings in the periodontal ligament. No immunoreactivity was seen in Schwann cells. The immunostaining results support the view that the beta 1-subunit of Na+/K(+)-ATPase is the predominant isoform in sensory neurones, and that this protein is a useful marker for periodontal Ruffini-like endings.

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Citations

Nov 17, 2010·Neuroscience Letters·Farhana RahmanTakeyasu Maeda
Jun 8, 2007·Brain Research·Batheegama Gammacharige Tharanga Lakmali NandasenaTakeyasu Maeda
Apr 12, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·T MaedaS Wakisaka

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