PMID: 6165728Jan 1, 1981Paper

Immunocytochemical demonstration of filamentous structures in the parotid gland. Occurrence of keratin and actin in normal and tumoral parotid gland with special respect to the myoepithelial cells

Journal of Cancer Research and Clinical Oncology
J CaselitzJ Thivolet

Abstract

The aim of this study was to analyze the filament distribution in the parotid gland and their tumors. A correlation to the histogenetic implications and histological properties was attempted. Normal rat and human parotid glands as well as pleomorphic adenomas and squamous cell carcinomas of this gland were examined by the indirect immunoperoxidase technique using antibodies to the keratin polypeptide of 67,000 dalton, and 55,000 dalton and anti-actin auto-antibodies. Both keratin and actin antigens were demonstrated in the duct system and in the myoepithelial cells of the normal salivary glands. The acinar cells remained negative. In pleomorphic adenomas, there were numerous keratin-positive spindle-shaped cells which represented the so-called myoepithelial cells. These cells were demonstrated to contain actin, too. The tubular duct-like structures were labeled by keratin antiserum and by anti-actin auto-antibodies. In squamous cell carcinomas, the majority of the tumor cells were strongly labeled by keratin antibodies. Actin was detected in these malignant cells, too. Our results show important differences in the cellular elements of the normal salivary glands with regard to their filament distribution. In normal and tumoral c...Continue Reading

References

Dec 1, 1979·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·D DrenckhahnU Gröschel-Stewart
Jan 1, 1976·Archives of Oto-rhino-laryngology·G Seifert, K Donath
Feb 1, 1970·British Journal of Preventive & Social Medicine·M P Prior
Mar 1, 1980·The Journal of Cell Biology·W W FrankeT W Keenan
Jan 1, 1980·Archives of Dermatological Research·J ViacC Goujon
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·J P OrtonneJ Thivolet
Feb 1, 1980·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G BussolatiM Osborn

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Citations

Jan 1, 1990·Histochemistry·P S ThraneP Brandtzaeg
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·J Caselitz, T Löning
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·S GeigerG Marshak
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·R M Palmer, J W Eveson
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·I DardickD L Brown
Apr 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·V C de AraujoN S de Araujo
Jun 1, 1986·International Journal of Oral and Maxillofacial Surgery·M HosakaM Mori
Nov 1, 1996·European Journal of Cancer. Part B, Oral Oncology·C H LeeM Mori
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·B A GustersonM G Ormerod
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·R Nilsen, K Donath
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·B GustersonJ Sloane
Jan 1, 1984·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·Y TakaiM Mori
Jan 1, 1982·Pathology, Research and Practice·P BannaschD Mayer
Jan 1, 1982·Journal of Oral Pathology·J CaselitzT Jaup
Aug 1, 1984·Journal of Oral Pathology·I DardickA W van Nostrand
Feb 1, 1983·Journal of Cutaneous Pathology·J Thivolet, M Faure
Oct 1, 1987·Journal of Oral Pathology·G Marshak, O Leitner
Jun 1, 1985·Histopathology·J M OrensteinA W van Nostrand
Jun 1, 1989·International Journal of Oral and Maxillofacial Surgery·N SegamiT Manabe
Jan 1, 1985·Ultrastructural Pathology·H W Huntington, I Dardick
Apr 14, 2006·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Bernard TandlerCarleton J Phillips
Jan 1, 1989·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·T NinomiyaK Tsukitani
May 1, 1989·Zentralblatt für Veterinärmedizin. Reihe A·J H VosM de Neijs
Jan 1, 1987·Critical Reviews in Clinical Laboratory Sciences·E J Raubenheimer
Jan 1, 1986·Virchows Archiv. A, Pathological Anatomy and Histopathology·H Hellquist, L Michaels
May 1, 1985·Head & Neck Surgery·I Dardick, A W van Nostrand

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