PMID: 6978331Nov 1, 1981Paper

Immunocytochemical detection of tumour markers in bone metastases from carcinoma of the breast

The Histochemical Journal
P GugliottaG Bussolati

Abstract

The value of immunocytochemical methods for detecting seven tumour-associated antigens was assessed in ten cases of bone metastases from carcinoma of the breast. In order to obtain the optimal preservation of both their structure and antigenicity, the biopsies were fixed-decalcified in Bouin's fluid by means of an apparatus based on ion-exchange resins recently developed in this laboratory. Of the different tumour markers, milk fat globule membrane antigen and carcino-embryonic antigen were found to be present in the majority of the cases of neoplastic cells. These two markers appear, therefore, to be the most useful for the immunocytochemical identification of metastatic neoplastic cells in the bone marrow originating from carcinoma of the breast.

References

Aug 2, 1975·Lancet·K Landys, U Stenram
Aug 13, 1977·Lancet·G BussolatiG F Voglino
Oct 1, 1979·Journal of Clinical Pathology·E Heyderman
Jan 1, 1975·Virchows Archiv. A, Pathological Anatomy and Histology·G BussolatiV Alfani
Sep 1, 1979·The Journal of Pathology·R A Walker
Feb 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R L CerianiS Abraham
Sep 1, 1978·Histopathology·G Bussolati
May 1, 1979·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D H CoveA Howell
Mar 24, 1979·British Medical Journal·S ShoushaP J Scheuer
Sep 1, 1979·Histopathology·V EusebiG Bussolati
Aug 1, 1976·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A PichA Carbonara
Apr 1, 1966·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R C Graham, M J Karnovsky

❮ Previous
Next ❯

Citations

Mar 1, 1985·European Journal of Cancer & Clinical Oncology·A M Neville, B A Gusterson
Jan 1, 1987·Cancer Investigation·A C Hollinshead
Apr 7, 2016·American Journal of Public Health·Michael S Chen, San-Kuei Huang
Feb 3, 2004·The Oncologist·Eric T Wong, Anna Berkenblit

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.