PMID: 8590274Jan 1, 1995Paper

Immunocytochemical localization of prostaglandin E2 receptor subtypes in porcine ocular tissues. I. Uveal tissues

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
C ZhaoH Shichi

Abstract

Polyclonal antibodies were raised against 15-residue sequences in the carboxyl terminal region of mouse EP1, EP2, and EP3 subtypes. The selected sequences are well conserved in different species. Using the antibodies, the localization of the receptor subtypes in porcine uveal tissues was investigated by immunoperoxidase reaction (by light microscopy) and immunogold labeling (by electron microscopy). EP1 immunoreactivity was found in ciliary nonpigmented epithelium and iris muscles (both sphincter and dilator). EP2 was localized to ciliary nonpigmented epithelium and muscle, iris sphincter muscle, and trabecular meshwork. EP3 immunoreactivity was detected in all uveal tissues examined.

References

Jan 1, 1992·Journal of Ocular Pharmacology·T AsakuraH Shichi
Oct 1, 1991·Current Eye Research·S E Ohia, J E Jumblatt
Oct 1, 1991·Prostaglandins, Leukotrienes, and Essential Fatty Acids·A A Abdel-Latif
Jan 1, 1988·Journal of Ocular Pharmacology·A J Flach, J A Eliason
Aug 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·J P Tam
Feb 15, 1994·Biochemical and Biophysical Research Communications·J YangS An
Jan 1, 1994·Journal of Ocular Pharmacology·P Bhattacherjee, C A Paterson
Nov 30, 1993·Biochemical and Biophysical Research Communications·S AnE J Goetzl
Oct 1, 1993·Prostaglandins, Leukotrienes, and Essential Fatty Acids·N Sano, H Shichi
Jul 30, 1993·Biochemical and Biophysical Research Communications·K TakeuchiK Abe
Jan 23, 1957·The Journal of Physiology·N AMBACHE

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Citations

Mar 11, 1998·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·G L ZhanS E Ohia
Aug 27, 1999·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·T L Davis, N A Sharif
Apr 29, 2005·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Najam A SharifGary W Williams
Mar 22, 2008·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Zaher A Radi, James A Render
Dec 23, 1998·Proceedings of the National Academy of Sciences of the United States of America·M BhattacharyaS Chemtob
May 8, 2001·Seminars in Perinatology·A BouayadS Chemtob
Feb 3, 2005·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Naj A SharifTerry L Davis
Sep 24, 2004·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Sumana BiswasChristopher A Paterson
Mar 16, 2004·Veterinary Pathology·R S SellersK N M Khan
May 21, 1999·The Journal of Biological Chemistry·M BhattacharyaS Chemtob

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