Antisera to vertebrate actin and actin-binding proteins were used to characterize the cytoskeleton of adult Schistosoma mansoni. Actin, alpha-actinin and tropomyosin immunoreactivities were detected in the cytoplasm of the apical tegument. Antiserum to alpha-actinin bound to the tegumental spines and this protein may be involved in cross-linking of spine actin filaments. Actin, alpha-actinin and tropomyosin antisera bound to the musculature. Strongest immunoreactivity was seen in the parenchyma. Antisera to actin, alpha-actinin, tropomyosin and spectrin bound to parenchyma cells including those of the tubercles, suggesting that these proteins are located in muscle cell bodies. The distribution of cytoskeletal proteins is discussed in relation to tegumental repair processes.
Schistosoma mansoni: structural damage and tegumental repair after in vivo treatment with praziquantel
Schistosoma mansoni: changes in the outer membrane of the tegument during development from cercaria to adult worm
Studies in proline metabolism by Schistosoma mansoni. I. Radioautography following in vitro exposure to radioproline C14
Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation
Schistosoma mansoni: the effects of a subcurative dose of praziquantel on the ultrastructure of worms in vivo
Schistosoma mansoni: cellular reactions to challenge infections in the cheek pouch skin of chronically infected Chinese hamsters
Schistosoma mansoni: dose-related tegumental surface changes after in vivo treatment with praziquantel
Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation
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Fasciola hepatica: the effect of the microfilament inhibitor cytochalasin B on the ultrastructure of the adult fluke
Schistosoma mansoni: praziquantel-induced tegumental lesion exposes actin of surface spines and allows binding of actin depolymerizing factor, gelsolin
Proteomic analysis of schistosoma japonicum schistosomulum proteins that are differentially expressed among hosts differing in their susceptibility to the infection.
Human IgE responses to different splice variants of Schistosoma mansoni tropomyosin: associations with immunity
Immunolocalization of cytoskeletal components in the tegument of the 3-week-old juvenile and adult Fasciola gigantica
Alternative patterns of MHC-restricted antibody responsiveness following intraperitoneal immunization of inbred mice with different preparations of an 86 kilodalton antigen of Schistosoma mansoni
Identification of Candidate Serum Biomarkers for Schistosoma mansoni Infected Mice Using Multiple Proteomic Platforms
The cellular distribution and stage-specific expression of two dynein light chains from the human blood fluke Schistosoma japonicum
The cytoskeleton and motor proteins of human schistosomes and their roles in surface maintenance and host-parasite interactions
Actin-binding proteins are a component of the actin cytoskeleton that play essential roles in cellular functions such as regulation of actin polymerization, maintenance of cell polarity, gene expression regulation, cell motility and many more functions. Discover the latest research on actin-binding proteins here.