Immunocytochemistry of histamine in the brain of the locust Schistocerca gregaria

Cell and Tissue Research
Stephan Gebhardt, Uwe Homberg

Abstract

Histamine serves a neurotransmitter role in arthropod photoreceptor neurons, but is also present in a small number of interneurons throughout the nervous system. In search of a suitable model system for the analysis of histaminergic neurotransmission in insects, we mapped the distribution of histamine in the brain of the desert locust Schistocerca gregaria by immunocytochemistry. In the optic lobe, apparently all photoreceptor cells of the compound eye with projections to the lamina and medulla showed intense immunostaining. Photoreceptors of the dorsal rim area of the eye had particularly large fiber diameters and gave rise to uniform varicose immunostaining throughout dorsal rim areas of the lamina and medulla. In the locust midbrain 21 bilateral pairs of histamine-immunoreactive interneurons were found, and 13 of these were reconstructed in detail. While most neuropil areas contained a dense meshwork of immunoreactive processes, immunostaining in the antennal lobe and in the calyces of the mushroom body was sparse and no staining occurred in the pedunculus and lobes of the mushroom body, in the protocerebral bridge, and in the lower division of the central body. A prominent group of four immunostained neurons had large cell ...Continue Reading

Citations

Oct 7, 2015·The Journal of Comparative Neurology·Andreas ArendtMonika Stengl
May 29, 2007·Progress in Neurobiology·Ann E StuartIan A Meinertzhagen
Oct 31, 2006·The Journal of Comparative Neurology·Sebastian KirschnerWolfgang Rössler
Aug 10, 2011·The Journal of Comparative Neurology·Gerd LeitingerDagmar Kolb
Jun 10, 2010·The Journal of Comparative Neurology·Andrew M DacksAlan J Nighorn
Sep 5, 2014·The Journal of Comparative Neurology·Alina GellererUwe Homberg
Mar 5, 2010·Journal of Neurophysiology·Daniel JanssenEmmy Van Kerkhove
Dec 20, 2013·Proceedings. Biological Sciences·Martin J How, N Justin Marshall
Oct 19, 2019·The Journal of Comparative Neurology·Joss von HadelnUwe Homberg
Jul 28, 2017·Proceedings. Biological Sciences·Phillip D ChapmanAndrew M Dacks
Feb 27, 2015·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Fabian SchmelingUwe Homberg

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