Abstract
Infections of the upper respiratory tract are common to both the immunodeficient and the normal child during their development. The most common head and neck manifestations of immunodeficiency disease are recurrent suppurative otitis media, tonsillitis, sinusitis, rhinitis, and nasopharyngitis. Often the head and neck specialist is confronted with a child with one or more of these problems and must institute the appropriate therapy or decide on an avenue for further investigation. This paper outlines the major immunodeficiency state, discusses the immune defects thought to be responsible for the spectrum of clinical findings, and suggests a systematic approach to the evaluation of these difficult diseases. The recognition of immunodeficient individuals is an important step in their treatment so that adjunctive immunological therapy can be provided.
References
Jan 1, 1979·American Journal of Otolaryngology·C P Kimmelman, W P Potsic
Dec 23, 1976·The New England Journal of Medicine·J A GelfandM M Frank
Jul 1, 1977·The Journal of Allergy and Clinical Immunology·A L ShefferF S Rosen
Jul 1, 1976·The Journal of Clinical Investigation·F P SiegalR A Good
Jul 1, 1976·The Journal of Clinical Investigation·R H BuckleyT A Waldmann
Sep 1, 1976·Acta Oto-laryngologica·P BerdalS Skrede
May 1, 1976·Annals of Internal Medicine·M M FrankJ P Atkinson
Sep 14, 1974·Lancet·T A WaldmannW Strober
Oct 1, 1967·American Journal of Diseases of Children·R B Johnston, J S McMurry
Jul 4, 1974·The New England Journal of Medicine·R S GehaF S Rosen
May 24, 1974·Nature·J J OwenM C Raff
Oct 19, 1972·The New England Journal of Medicine·R W SteeleJ A Bellanti
Jan 1, 1966·The Journal of Experimental Medicine·M D CooperR A Good
Feb 1, 1981·Archives of Otolaryngology·C T SasakiE Yanagisawa
Dec 1, 1957·A.M.A. Journal of Diseases of Children·A R PAGE, R A GOOD
Citations
Oct 23, 2008·Current Allergy and Asthma Reports·Nevin W Wilson, Mary Beth Hogan
Nov 1, 1984·The Laryngoscope·D E Schuller
Dec 6, 2006·The Laryngoscope·Rodney P LuskJay Piccirillo
Oct 22, 2003·Otolaryngologic Clinics of North America·Andrew G Sikora, Kelvin C Lee
Feb 1, 1984·The Journal of the American Dental Association·R ChuongR E Fechner
Apr 24, 1999·The Annals of Otology, Rhinology, and Laryngology·R M StocksE Simms