PMID: 9640680Jul 1, 1997Paper

Immunodiagnosis in 647 suspected clinical cases of toxoplasmosis

Boletín chileno de parasitología
M C ContrerasH Schenone

Abstract

Though Toxoplasma gondii can cause severe pathology in human, in most of the cases it produces only asymptomatic infection. So, it is important to dispose some methods capables to discriminate between acute and chronic infections. An indirect hemagglutination test (IHAT), dye test (DT) and complement fixation test (CFT) were performed in 647 sera from patients suspected of having toxoplasmosis infection. IHAT and DT titer > or = 4 and CFT > or = 5 were considered positive. Titers were classified as follows: low (4-16), median (64-512) and high (> or = 1000) for IHAT and DT. The pathologies for demanding these serological tests were: adenopathies (58), nephropathies (72), neuropathies (30), obstetrical problems (65), opthalmopathies (147), AIDS (237) and miscellaneous (37). Global positivity of 49.5% and 4.5% for IHAT/DT and CFT respectively were found. The positivity for the different groups were: adenopathies (48.3% and 13.8%), nephropathies (43.1% and 1.4%), neuropathies (26.7% and 3.3%), obstetrical problems (40.0% and 0.0%), ophthalmopathies (59.9% and 8.2%), AIDS (52.1% and 2.5%) and miscellaneous (40.5% and 2.7%) for IHAT/DT and CFT respectively. Low and median titers for IHAT/DT were found in 81.3% of cases. A high agree...Continue Reading

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