PMID: 7017534May 1, 1981Paper

Immunofluorescent study of cytologic smears in oral pemphigus: A simple diagnostic technique

Oral Surgery, Oral Medicine, and Oral Pathology
G LaskarisA Angelopoulos

Abstract

This study was undertaken in order to explore the diagnostic efficacy of the direct immunofluorescent technique for demonstration in vivo bound immunoglobulins to desquamated epithelial cells from patients with oral pemphigus. Cytologic smears were obtained with a wooden spatula from the oral lesions of thirty patients with known pemphigus vulgaris. Control smears were taken from thirty-five patients twenty suffering from various other mucosal diseases and fifteen devoid of oral lesions. The smears were stored at -30 degrees C. and prepared within 48 hours for examination by the direct immunofluorescent technique. Deposition of IgG was demonstrated in all thirty smears from the oral pemphigus lesions. None of the control smears gave positive results. These findings suggest that the direct immunofluorescent technique using cytologic smears may provide an additional simple and reliable method in the diagnosis or oral pemphigus vulgaris.

References

Oct 1, 1975·International Journal of Oral Surgery·M SchiödtI C MacKenzie
Jul 1, 1976·Archives of Dermatology·F R RosenbergC T Nelson
Sep 1, 1975·Oral Surgery, Oral Medicine, and Oral Pathology·R J NisengardG Rzesa
Jul 1, 1971·Archives of Dermatology·J G Ryan

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Citations

Jul 1, 1997·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M D MignognaE Bucci
Jun 1, 1983·International Journal of Oral Surgery·H YamamotoR Shimokawa
Dec 1, 1984·The Journal of Dermatology·V RuoccoM Pisani
Jun 1, 1983·Journal of Oral Pathology·J S Greenspan
Feb 1, 1997·Diagnostic Cytopathology·T K KobayashiS Watanabe
Sep 19, 2021·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Wenxiu HePan Wei

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