Immunoglobulin deficiency in patients with chronic rhinosinusitis: Systematic review of the literature and meta-analysis

The Journal of Allergy and Clinical Immunology
Adrien J-P SchwitzguébelThomas Harr

Abstract

Several studies have shown a high prevalence of immunoglobulin deficiencies in patients with chronic rhinosinusitis (CRS). We sought to perform a systematic review and meta-analysis to estimate this prevalence more precisely and to identify patients who need substitution treatment. All case series published after 1990 describing patients with CRS, which was defined as symptomatic rhinosinusitis for more than 12 weeks and documented immunoglobulin deficiencies (including deficiencies of IgG with subclasses, IgA, and IgM; specific antibody deficiencies; and potential common variable immunodeficiency), were retrieved. A meta-analysis of the proportion of any combination of common variable immunodeficiency, IgG deficiency, IgA deficiency, and IgM deficiency in patients with CRS was performed by using logit transformation of the prevalence. Recurrent CRS was defined as rhinosinusitis not controlled by appropriate conservative management for 4 months, and difficult-to-treat CRS was defined as noncontrollable rhinosinusitis despite successful sinus surgery and appropriate conservative management for at least 1 year. The meta-analysis revealed a prevalence of pooled IgG, IgA, and IgM deficiencies in 13% of patients with recurrent CRS a...Continue Reading

References

Aug 1, 1988·Archives of Otolaryngology--head & Neck Surgery·T E HavasP J Gullane
Apr 1, 1996·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·H HidalgoR U Sorensen
Dec 1, 1996·The Journal of Pediatrics·G LackE W Gelfand
Jun 1, 1997·Archives of Otolaryngology--head & Neck Surgery·Y IwabuchiS Furuta
Aug 1, 1997·The Journal of Allergy and Clinical Immunology·G E HooverL M Wheatley
Nov 7, 1999·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A MayA Weber
Feb 24, 2001·The Laryngoscope·L CheeZ K Ballas
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
May 13, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Rong-San Jiang, Chen-Yi Hsu
Apr 5, 2005·The Journal of Allergy and Clinical Immunology·Xavier BossuytKris De Boeck
Jun 11, 2005·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Francisco A BonillaUNKNOWN Joint Council of Allergy, Asthma and Immunology
Aug 2, 2006·Clinical and Experimental Immunology·M SeppänenV Valtonen
Dec 15, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Todd A LevinChristine C Johnson
Jun 20, 2007·Journal of Clinical Immunology·J M Boyle, R H Buckley
Jul 15, 2009·Clinical Microbiology Reviews·Ari J Fried, Francisco A Bonilla
Dec 17, 2009·The Journal of Allergy and Clinical Immunology·UNKNOWN International Union of Immunological Societies Expert Committee on Primary ImmunodeficienciesJosiah Wedgwood
Aug 21, 2010·American Journal of Otolaryngology·Richard L Wasserman, Scott C Manning
Dec 15, 2010·American Journal of Rhinology & Allergy·Mohannad AlqudahZuhair K Ballas
Dec 31, 2010·Current Opinion in Otolaryngology & Head and Neck Surgery·Kristin Woodbury, Berrylin J Ferguson
Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Neil BhattacharyyaMelissa Martinson
Aug 9, 2011·American Journal of Rhinology & Allergy·Tara F CarrAnju T Peters
Sep 6, 2011·The Journal of Allergy and Clinical Immunology·Daniel L Hamilos
Dec 20, 2011·Blood·Elena S ResnickCharlotte Cunningham-Rundles
Jan 1, 2011·Clinical and Translational Allergy·Hoàng Thị LâmBo Lundbäck
Feb 15, 2013·American Journal of Rhinology & Allergy·Christopher J Ocampo, Anju T Peters
Apr 2, 2013·The Journal of Allergy and Clinical Immunology·Erwin W GelfandWilliam T Shearer
Dec 12, 2013·Expert Review of Clinical Immunology·Mikko SeppänenNima Rezaei
Mar 4, 2014·The Journal of Allergy and Clinical Immunology·Benjamin GathmannUNKNOWN European Society for Immunodeficiencies Registry Working Party

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Citations

Mar 16, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Haitham Odat, Mohannad Alqudah
Jul 10, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Sumit BoseAnju T Peters
Jul 10, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Robert M Naclerio, Fuad M Baroody
Aug 9, 2016·Expert Review of Clinical Immunology·Sergio E Chiarella, Leslie C Grammer
Aug 24, 2016·Journal of Korean Medical Science·Joo Hee KimDong Gyu Kim
Nov 8, 2016·The Journal of Allergy and Clinical Immunology·Claus Bachert, Elien Gevaert
Jul 13, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Katie M PhillipsAhmad R Sedaghat
Sep 3, 2016·The European Respiratory Journal·William J JanssenChristopher M Evans
Mar 29, 2019·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Wojciech FeleszkoJosé Luis Mayorga Butrón
May 10, 2019·Journal of Clinical Medicine·Emilie BequignonJean-François Papon
Aug 5, 2017·Current Allergy and Asthma Reports·Rahuram Sivasubramaniam, Richard J Harvey
Mar 23, 2018·Allergo Journal International·Michael KoenneckeBarbara Wollenberg
Sep 19, 2019·American Journal of Rhinology & Allergy·Carol LiAaron N Pearlman
Jan 29, 2020·Expert Review of Clinical Immunology·Chengshuo WangLuo Zhang
Jun 3, 2016·Current Opinion in Allergy and Clinical Immunology·Andrew J ParaAnju T Peters
Jul 16, 2020·International Forum of Allergy & Rhinology·Shireen SamargandyJonathan Yip
Jul 4, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Katie M PhillipsAhmad R Sedaghat
Dec 6, 2019·Ear, Nose, & Throat Journal·Rafaela Veloso-TelesChristian von Buchwald
May 21, 2020·Current Allergy and Asthma Reports·Justin P McCormickJessica W Grayson
Nov 10, 2020·Current Opinion in Allergy and Clinical Immunology·Luke N BaileyJessica W Grayson
May 8, 2018·The Journal of Allergy and Clinical Immunology·Bruce K TanKathryn E Hulse
Nov 26, 2020·International Forum of Allergy & Rhinology·Richard R OrlandiBing Zhou
Jun 2, 2021·Clinical and Experimental Immunology·Emanuele VivarelliAlessandra Vultaggio

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