Immunoglobulin E- (IgE) and non-IgE-mediated reactions in the pathogenesis of atopic eczema/dermatitis syndrome (AEDS)

Allergy
E J Bardana

Abstract

AEDS is a chronic, relapsing, highly pruritic inflammatory skin disease that commonly begins in childhood. Two forms of this disorder exist, i.e. an allergic (extrinsic) form and a nonallergic (intrinsic) form. There are clear genetic, humoral and cellular differences between the allergic and nonallergic forms of AEDS. The allergic variants express local IgE production in affected tissue and both allergic and nonallergic triggers play a major role in the expression of disease. The role of allergens is very important in the immunopathogenesis of AEDS. Nonimmunological triggers play a secondary modulatory role often hampering treatment effort and optimal response to therapeutic efforts.

References

Jul 1, 1991·The British Journal of Dermatology·D Kemmett, M J Tidman
Sep 1, 1991·The British Journal of Dermatology·M W WesselsE Young
Dec 1, 1989·The British Journal of Dermatology·A Giannetti, G Girolomoni
Feb 1, 1989·The British Journal of Dermatology·H I Beck, J Korsgaard
Feb 1, 1984·The Journal of Allergy and Clinical Immunology·J M Hanifin
May 1, 1996·The Journal of Allergy and Clinical Immunology·R A TupkerJ B van der Meer
May 18, 1999·The Journal of Allergy and Clinical Immunology·H A Sampson
Jun 22, 1999·Current Problems in Dermatology·C A AkdisH U Simon
Sep 14, 1999·The Journal of Allergy and Clinical Immunology·S H Sicherer, H A Sampson
Oct 3, 1999·The Journal of Investigative Dermatology·C A AkdisH U Simon
Dec 3, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·B Wüthrich
Dec 10, 1999·The Journal of Allergy and Clinical Immunology·T SchäferH E Wichmann
Feb 7, 2001·Allergy·A Wollenberg, T Bieber
May 16, 2000·The Journal of Allergy and Clinical Immunology·D Y Leung
Jun 16, 2000·The Journal of Allergy and Clinical Immunology·R L OchsE M Tan
Sep 12, 2001·Allergy·S G JohanssonUNKNOWN EAACI (the European Academy of Allergology and Cinical Immunology) nomenclature task force
Mar 22, 2002·Allergy·B Wüthrich, P Schmid-Grendelmeier
Jul 9, 2003·The Journal of Allergy and Clinical Immunology·Natalija NovakThomas Bieber
Aug 5, 2003·The Journal of Allergy and Clinical Immunology·Natalija Novak, Thomas Bieber

❮ Previous
Next ❯

Citations

Oct 12, 2005·Current Allergy and Asthma Reports·James L Sublett
Aug 30, 2008·Immunologic Research·Daniel P PotaczekKo Okumura
Feb 5, 2015·Molecular Medicine Reports·Lin DangYuzhen Li
Jun 3, 2015·International Journal of Molecular Medicine·Hyun YangEui-Bae Jeung
Apr 29, 2015·Journal of the European Academy of Dermatology and Venereology : JEADV·Z SongF Hao
Feb 28, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T W SongK-E Kim
Dec 2, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·T Groot KormelinkF A Redegeld
Oct 31, 2009·Clinical and Experimental Dermatology·H M JeeK E Kim
May 7, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Eun Byoul LeeKyu-Earn Kim
Mar 23, 2017·Epigenomics·Daniel P PotaczekJörg Tost
Feb 28, 2020·Drug Delivery and Translational Research·Rehan Al-KasasbehRyan F Donnelly
Jul 20, 2010·Journal of Pediatric Gastroenterology and Nutrition·Vito Leonardo MinielloRuggiero Francavilla

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Journal of the American Academy of Dermatology
William Abramovits
Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research
Hideaki WatanabeDaniel N Sauder
© 2022 Meta ULC. All rights reserved