Immunoglobulin G4-Related Sclerosing Disease Manifesting as Bilateral Tonsillar Hypertrophy on MR Images: A Case Report

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Mee Hyun ParkMin Eui Hong

Abstract

Immunoglobulin G4-related sclerosing disease (IgG4-SD) is currently recognized as a distinct systemic disease involving various organs. We reported the imaging findings of a case of pathologically confirmed IgG4-SD involving bilateral palatine tonsils. CT and MRI showed diffuse enlargement of both palatine tonsils with homogeneous contrast enhancement. Focal contour bulging was noted in the right palatine tonsil. Lesions appeared as isointense on T1-weighted and slightly hyperintense on T2-weighted MRI images, as compared with muscle. The T2-weighted MRI image showed a striated pattern in both tonsils. Despite its rare occurrence, IgG4-SD should be included in the differential diagnoses of patients with symptomatic bilateral tonsillar hypertrophy that is non-responsive to medication.

References

Mar 10, 2001·The New England Journal of Medicine·H HamanoK Kiyosawa
Nov 14, 2003·Journal of Gastroenterology·Terumi KamisawaHitoshi Nakajima
Jul 9, 2008·World Journal of Gastroenterology : WJG·Terumi Kamisawa, Atsutake Okamoto
Apr 1, 2011·Journal of Gastroenterology·Kazuichi OkazakiMakoto Takaoka
Sep 16, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Paraskevi A VlachouTae Kyoung Kim
Feb 24, 2012·Neuroradiology·Masaki KatsuraKuni Ohtomo
Aug 21, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Syed Ali KhurramKeith D Hunter
Nov 3, 2012·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jin Woo ChoiSeung Hyup Kim
Sep 18, 2013·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Younghwan KoSeon Jeong Min
Feb 6, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Bruno CoulierIsabelle Gielen
Jul 16, 2015·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Michele RossiMarco Cavallini

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