PMID: 22568145May 10, 2012Paper

Immunoglobulin preparations

Nihon rinsho. Japanese journal of clinical medicine
Yasuo Ono

Abstract

Intravenous immunoglobulin (IVIG) preparation contains the antibodies to protect against the infectious agents that cause various diseases. IVIGs have become increasingly important both as replacement therapy in primary and acquired humoral immunodeficiency and as an immunomodulatory therapy in autoimmune diseases. At present, the use of IVIGs for prevention against viral infections has been proven beneficial only for a limited number of infections such as measles, varicella, hepatitis A, hepatitis B. The addition of high-dose IVIG to ganciclovir appears to be useful for treatment of Cytomegalovirus pneumonia following bone marrow transplantation.

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