Immunoglobulin superfamily members gp65 and gp55: tissue distribution of glycoforms

FEBS Letters
Kristina LangnaesePhilip Beesley

Abstract

Gp65 and gp55 are immunoglobulin superfamily members produced by alternative splicing of the same gene transcript, and originally identified as components of synaptic membranes. A monoclonal antibody specific for gp65 and gp55 has been used to detect immunoreactive species in a wide range of tissues. All immunoreactive species bind to concanavalin A and deglycosylation studies show that in all tissues tested other than brain the immunoreactive species are derived from gp55. HEK cells transfected with gp65 or gp55 express different glycoforms from brain showing that the pattern of glycosylation of these molecules is dependent upon the cell type in which they are expressed.

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Citations

Jun 24, 2008·Cancer Immunology, Immunotherapy : CII·Daniel Rodriguez-PintoKevin P Claffey
May 29, 2012·Journal of Molecular Neuroscience : MN·Kristina MlinacSvjetlana Kalanj Bognar
Apr 12, 2000·Proceedings of the National Academy of Sciences of the United States of America·K H SmallaE D Gundelfinger
Aug 11, 2004·Proceedings of the National Academy of Sciences of the United States of America·Zhi-Jian SuJennifer R Gamble
Dec 23, 2015·Neurobiology of Learning and Memory·Siyiti AmutiQionglan Yuan
Jul 22, 2014·Journal of Neurochemistry·Philip W BeesleyConstanze Seidenbecher
Nov 1, 2011·The International Journal of Biochemistry & Cell Biology·Sylwia Owczarek, Vladimir Berezin
May 6, 2004·Brain Research. Developmental Brain Research·Lucy E BuckbyRuth M Empson
Dec 3, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Sylwia OwczarekVladislav Soroka
Aug 23, 2017·Scientific Reports·Mark KorthalsUlrich Thomas
Nov 30, 2018·Journal of Cellular and Molecular Medicine·Katarina IlicSvjetlana Kalanj-Bognar
Jul 21, 2021·Translational Psychiatry·Katarina IlicSvjetlana Kalanj-Bognar

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