PMID: 45711Jan 1, 1976

Immunoglobulins in the chronic phase of Chagas disease

Memórias do Instituto Oswaldo Cruz
G De FreitasJ G De Souza

Abstract

Since divergent results were obtained by different authors about immunoglobulins concentration in sera from acute and chronic cases of Chagas disease, the problem was submitted to statistical approach in field conditions in the endemic zone of Bambui, state of Minas Gerais, Brazil. Positives cases were considered in all individuals presenting evidences in parasitological, immunological or electrocardiographical examination living exactly in the same conditions, but without any evidence of infection under the same criteria. The sample consisted of 32 chronic cases and no significant difference in the immunoglobulins levels were detected in chronic cases of Chagas disease as compared with the control group. Heterophili antibodies are being determined in chronic cases and apparently there is no relationship between its concentration and pathogenic effects.

Related Concepts

Pathogenic Organism
Chagas Disease Pathway
Phosphoglycerate Dehydrogenase Activity
Immunoglobulins
IgA2
IgM2
PHGDH wt Allele
Trypanosoma cruzi
Polyglobin
Antibodies, Protozoan
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