Nov 15, 1977

Immunoglobulins, proteinase inhibitors, albumin, and lysozyme in human cervical mucus. I. Communication: hormonal profiles and cervical mucus changes--methods and results

American Journal of Obstetrics and Gynecology
G F SchumacherC Dupon

Abstract

The serum levels of luteinizing hormone (LH), estradiol-17beta, and progesterone were determined simultaneously with the concentrations of immunoglobulin (Ig) G, IgA, C'3, alpha1-antitrypsin, inter-alpha-trypsin inhibitor, alpha1x-antichymotrypsin, albumin, and lysozyme in cervical mucus during nine ovulatory cycles. Spinnbarkeit and ferning were also assessed, and the basal body temperature was measured and recorded during these cycles. The profiles were synchronized according to the LH peak. The midcycle period, characterized by the rapid increase and decline of estrogen and the beginning rise of progesterone, shows a prounced minimum of immunoglobulins, C'3, proteinase inhibitors, albumin, and lysozyme in cervical mucus, which is known to be most receptive to sperm penetration at this time. Although the variation of cervical mucus values is considerable during the early proliferative and the luteal phases, the midcycle values appear to be constantly low, showing slight differences among the profiles of the different parameters. The statistical evaluation and the assessment of the significance of parameters for ovulation detection and the assessment of the fertile period as well as the correlation of these parameters with bas...Continue Reading

  • References7
  • Citations15

References

  • References7
  • Citations15

Citations

Mentioned in this Paper

Fertility
SERPINA1 gene
Proteinase inhibitors, antifibrinolytic
Immunoglobulin Activity
Trypsin Inhibitors
Progesterone, (9 beta,10 alpha)-Isomer
Complement C3 precursor
Lysozyme Test
Estradiol, (16 alpha,17 beta)-Isomer
Ovulation

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