Immunohistochemical analysis of tissues regenerated from within periodontal defects treated with expanded polytetrafluoroethylene membranes

Journal of Periodontology
S Pritlove-CarsonP R Morgan

Abstract

Immunocytochemical analysis was carried out on samples of 5-, 6-, and 9-week old regenerated soft tissue taken from healing periodontal defects treated by guided tissue regeneration using expanded polytetrafluorethylene (ePTFE) membranes. A panel of monoclonal and polyconal antibodies to cytokeratins, vimentin, and collagen was used to label cells and collagen types I, III, and IV. Epithelium was identified in 7 of the 9 samples examined, in addition to mesenchymal cells staining positively for vimentin and co-distribution of collagen types I, III, and IV in all samples. Clinical observations indicated that exposure of the ePTFE membranes during healing was a frequent occurrence, and the presence and quantity of epithelium found within the healing defect beneath the membrane may be related to the extent to which this occurs.

References

Dec 1, 1992·Journal of Dental Research·L Häkkinen, H Larjava
Jul 1, 1990·Journal of Periodontal Research·J I Salonen, G R Persson
Jul 1, 1990·Journal of Clinical Periodontology·D J Pippin
Jul 1, 1986·Journal of Clinical Periodontology·J GottlowJ Wennström
Nov 1, 1987·Journal of Clinical Periodontology·R PontorieroF Sanavi

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Citations

Apr 20, 1999·Journal of Periodontal Research·L KuruI Olsen
Jul 16, 2008·Journal of Periodontal Research·N-H LinP M Bartold
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Robert A Convissar
Oct 7, 2004·Dental Clinics of North America·Stuart Coleton

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