Immunohistochemical Cross-Reactivity Between Paracoccidioides sp. from Dolphins and Histoplasma capsulatum

Mycopathologia
Godai ShumotoAyako Sano

Abstract

Paracoccidioidomycosis ceti is a cutaneous disease of cetaceans caused by uncultivated Paracoccidioides brasiliensis or Paracoccidioides spp. Serological cross-reactions between paracoccidioidomycosis ceti and paracoccidioidomycosis, paracoccidioidomycosis and histoplasmosis, and paracoccidioidomycosis and coccidioidomycosis have been reported before. The present study aimed to detect immunohistochemical cross-reaction between antibodies to Paracoccidioides sp. and Histoplasma capsulatum, and vice versa. Thirty murine sera, obtained from experimental infections of 6 isolates of H. capsulatum, were reacted with paraffin-embedded yeast-form cells of Paracoccidioides sp. derived from a case of paracoccidioidomycosis ceti in Japan. The murine sera were also reacted with human isolates of H. capsulatum yeast cells, with P. brasiliensis yeast cells, and with fungal cells of Coccidioides posadasii. Three dolphins' sera from cases of paracoccidioidomycosis ceti, two human sera from patients with paracoccidioidomycosis, and a serum from a healthy person with a history of coccidioidomycosis were used in order to determine that the tested fungal cells reacted properly. Sera derived from mice infected with an isolate of H. capsulatum react...Continue Reading

References

Jun 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J WheatA Restrepo
Aug 26, 1998·Journal of Wildlife Diseases·T H ReidarsonJ McBain
Apr 4, 2003·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Katsuhiko KameiMakoto Miyaji
Nov 15, 2003·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Shahana SharminMakoto Miyaji
Apr 1, 2009·Emerging Infectious Diseases·David S RotsteinAnn Pabst
Jan 26, 2010·Actas dermo-sifiliográficas·M Ramos-E-SilvaS Coelho-Carneiro
Aug 16, 2011·Medical Mycology·Fernando EsperónJosé Manuel Sánchez-Vizcaíno
Mar 21, 2012·Mycoses·A Paniz-MondolfiM F Van Bressem
Apr 27, 2012·Revista Da Sociedade Brasileira De Medicina Tropical·Fabrine Sales Massafera TristãoEiko Nakagawa Itano
Jun 12, 2012·Clinics in Dermatology·Sinésio Talhari, Carolina Talhari
Apr 11, 2013·Mycopathologia·Jacqueline B FerreiraMario A Ono
Aug 8, 2013·Vector Borne and Zoonotic Diseases·John S ReifGregory D Bossart
Jan 17, 2014·Diseases of Aquatic Organisms·Marie-Francoise Van BressemLeela Rajamani
Aug 19, 2015·Current Tropical Medicine Reports·Nathan C BahrGeorge A Sarosi
Nov 18, 2015·Diseases of Aquatic Organisms·Marie-Françoise Van BressemKoen Van Waerebeek
Jan 14, 2016·Diseases of Aquatic Organisms·Carlos SacristánJosé Luiz Catão-Dias
Jun 2, 2016·PLoS Neglected Tropical Diseases·Marcus de M TeixeiraBridget M Barker
Nov 22, 2016·Emerging Infectious Diseases·Raquel VilelaLeonel Mendoza
Jun 13, 2017·Fungal Genetics and Biology : FG & B·David A TurissiniDaniel R Matute
Dec 6, 2017·Transboundary and Emerging Diseases·C SacristánJ L Catão-Dias

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Datasets Mentioned

BETA
AB176477
AB176484
AB176486
AB055248
GMS

Methods Mentioned

BETA
light microscopy
antigen assay

Software Mentioned

BLAST

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