Abstract
A panel of monoclonal antibodies (mAb) and some polyclonal rabbit sera directed against human antigens were studied on cryostat tissue sections of three cats using immunohistochemistry. Reactivity of the antibodies was tested on feline tonsil, intestine, thymus, lymph node and spleen with a three-step immunoperoxidase technique and compared with reactions on human thymus, lymph node and spleen. From a total of 95 antibodies, 28 gave reactivity comparable with that in human tissues. The remaining antibodies gave none or miscellaneous results. The positive reactions in the cat included antibodies directed to adhesion molecules (VLA-2 and VLA-4), to natural killer (NK) cells (CD56, CD57 and NCAM), to complement receptor CR1, to proliferation marker Ki-67 (MIB-1), to endothelial antigens (EN-4, PAL-E and von Willebrand factor) and to structural proteins like vimentin, desmin, collagen type IV and cytokeratin. The identification of these cross-reacting antibodies extends the spectrum of immunological reagents that are now available for the cat, and will thus contribute to the study of the feline immune system.
References
Dec 1, 1992·Veterinary Immunology and Immunopathology·J J CallananO Jarrett
Jul 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·A E PeastonK A Sokol
Oct 1, 1992·Cell and Tissue Research·K FriedL Olgart
Dec 1, 1992·AIDS Research and Human Retroviruses·P JolingH J Schuurman
May 1, 1991·Antiviral Research·M B Gardner
Jan 1, 1990·Journal of Comparative Pathology·J H VosT S van den Ingh
Dec 1, 1990·Veterinary Immunology and Immunopathology·M B TompkinsW A Tompkins
Jan 1, 1990·AIDS·O JarrettJ C Neil
Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·H EgberinkM Koolen
Jul 1, 1988·Veterinary Immunology and Immunopathology·B AastedA Uttenthal
Apr 1, 1988·Veterinary Immunology and Immunopathology·M A HortonD Onions
Feb 13, 1987·Science·N C PedersenJ K Yamamoto
Mar 1, 1994·Veterinary Pathology·L W PaceJ R Fischer
May 1, 1995·Veterinary Immunology and Immunopathology·D MatteucciM Bendinelli
May 1, 1994·Research in Virology·C TsagarakisD Schmitt
Aug 1, 1994·Immunology Today·S CobboldB Willett
Mar 1, 1994·AIDS Research and Human Retroviruses·C M JohnsonJ K Yamamoto
May 1, 1994·Veterinary Pathology·P H Rowland, R P Linke
Apr 1, 1993·Current Opinion in Immunology·A M Kruisbeek
Mar 1, 1993·Veterinary Pathology·F Colbatzky, W Hermanns
Citations
Feb 26, 2011·Journal of Feline Medicine and Surgery·Valentina GreciEleanor C Hawkins
Jul 10, 1998·Veterinary Immunology and Immunopathology·R BrodersenB Aasted
Feb 26, 2000·Veterinary Immunology and Immunopathology·K M ByrneM G Hayek
Jul 13, 2001·Anatomia, histologia, embryologia·U Sommer, M Kressin
Nov 30, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·M HenrichM Reinacher
Feb 6, 2014·Journal of Feline Medicine and Surgery·Corma Ma OtteSandra Vreman
Mar 15, 2011·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Veronica L ScottKaren S Coats
Jul 10, 2002·Veterinary Pathology·F MillantaA Poli
Nov 21, 1998·Veterinary Pathology·K A Schafer
Mar 20, 2004·The Veterinary Record·K EzuraK Kadota
Aug 11, 2004·The Journal of General Virology·Yorihiro NishimuraTakayuki Miyazawa
Jul 20, 2019·JFMS Open Reports·Miyuki HirabayashiKazuyuki Uchida