Immunohistochemical detection of human milk components aspirated in lungs of an infant

Forensic Science International : Synergy
K IwadateT Takatori

Abstract

We examined an autopsy case of an infant whose cause of death was suspected to be asphyxia due to human breast milk aspiration. In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eight antibodies reacted positively with the substances suspected to be aspirated milk. We concluded that immunohistochemical staining with these antibodies is useful to demonstrate human milk aspiration and provide some keys for detecting the causes of unexpected infant deaths.

References

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Citations

May 10, 2000·Forensic Science International : Synergy·K IwadateH Hasekura
Feb 22, 2011·Forensic Science International : Synergy·Tomonori NagaiKimiharu Iwadate
Mar 6, 2010·Journal of Cutaneous Pathology·Erin G AdamsLeonard C Sperling
Oct 8, 2020·World Journal of Clinical Cases·Aniello MaieseVittorio Fineschi

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