PMID: 2494801Jan 1, 1989Paper

Immunohistochemical differentiation between lymphangiographically verified lymphatic vessels and blood vessels

Virchows Archiv. A, Pathological Anatomy and Histopathology
B M Hultberg, H Svanholm

Abstract

In order to investigate the antigen profile in human lymphatic vessels when compared with blood vessels, postmortem retrograde lymphangiography was done via the thoracic duct on six patients. Formalin fixed, paraffin embedded tissue was stained immunohistochemically for Factor VIII-Related antigen (F VIII R:Ag), with Ulex Europaeus 1 lectin (UEA-1) and for laminin. The results show that the endothelium of blood vessels and lymphatics at all levels of the lymphatic system react positively following staining for Factor VIII-R:Ag and with UEA-1 lectin. The staining for F VIII R:Ag was generally weaker in the endothelial cells lining lymphatic vessels. Staining for the basement membrane component laminin can be used to distinguish lymphatic capillaries and smaller lymphatic collecting vessels from blood vessels.

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Citations

Jan 1, 1991·Rheumatology International·L S Wilkinson, J C Edwards
Oct 14, 2003·Journal of Comparative Pathology·G D MansourA M R Ferreira
Jan 1, 1993·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M E Van HoefA M Schor
Apr 1, 1995·Journal of Clinical Pathology·E E MooneyD O Hourihane
Jan 5, 2006·Journal of Biomedical Materials Research. Part a·Gavin JellNajat Al-Saffar
Feb 13, 2001·Microvascular Research·N EbataS Yoshida
Oct 12, 2001·Microscopy Research and Technique·J P SleemanP Baumann
Aug 4, 2007·Virchows Archiv : an International Journal of Pathology·K WilliamsN A Athanasou
Dec 18, 2002·Acta Ophthalmologica Scandinavica·Jørgen Krohn, Eyvind Rødahl

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