Abstract
To identify keratin, the immunoperoxidase technique was performed on 41 nontumourous pituitaries, 14 pituitary adenomas composed of different cell types and 15 craniopharyngiomas. No keratin was demonstrated in adenohypophysial cells, neurohypophysis or hypophysial vessels, however, it was occasionally identified in the pairs intermedia within cells lining cystic structures. Crooke's hyaline material and all pituitary adenomas were negative for keratin. The epithelial portions of craniopharyngiomas exhibited positive keratin immunostaining, as did squamous cell nests, which are frequently found in hypophysial stalk. Immunostaining for keratin can effectively be used in the differential diagnosis of pituitary tumours and may prove valuable in the investigation of histogenesis and embryology.
References
Jan 1, 1978·Cancer·J J Kepes
Sep 15, 1978·Acta Neuropathologica·T LiszczakP L Kornblith
Mar 1, 1976·The British Journal of Radiology·M Banna
Apr 1, 1976·Cancer·C K PetitoK M Earle
Jun 1, 1971·Cancer·N R GhatakH M Zimmerman
Jan 1, 1974·Acta Anatomica·K KovacsC Ezrin
Oct 1, 1965·Journal of Neurosurgery·J U TogliaE Alexander
Citations
Feb 1, 1992·Cell and Tissue Research·T Shimada
Nov 1, 1991·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·C ZimmerJ Cervos-Navarro
Jan 1, 1986·Critical Reviews in Clinical Laboratory Sciences·A BoritB A Kakulas
Nov 1, 1987·Veterinary Pathology·W Baumgärtner, P V Peixoto
Jun 1, 1984·Journal of Neurosurgery·J M Bonnin, L J Rubinstein
Jan 1, 1994·Journal of Neurosurgery·O TachibanaY Takabatake
Jun 15, 1995·Cancer·H YamadaT Oda
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·J J KepesR Hiszczynskyj
Dec 1, 1988·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·T Shimada, F Nakamura
Apr 1, 1988·Cancer·H Mannoji, L E Becker
Oct 6, 1997·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·K V Badger, D G Gardner
Dec 1, 1991·Endocrine Pathology·Fernando MarinKalman Kovacs
Jan 16, 2007·Acta Neuropathologica·Rolf BusleiIngmar Blümcke
Jan 1, 1983·Virchows Archiv. A, Pathological Anatomy and Histopathology·S L AsaJ M Bilbao
May 16, 2002·Histopathology·P G Chu, L M Weiss
Nov 1, 1983·Clinics in Endocrinology and Metabolism·S L Asa, K Kovacs