PMID: 19926940Nov 21, 2009Paper

Immunohistochemical localization of steroidogenic enzymes in the testis of the sika deer (Cervus nippon) during developmental and seasonal changes

The Journal of Reproduction and Development
Daisuke HayakawaNobuo Kitamura

Abstract

Testicular steroidogenesis and spermatogenesis during developmental and seasonal changes were investigated in male sika deer (Cervus nippon), a short-day seasonal breeder, to clarify the physiological mechanisms for reproductive function. The immunohistochemical localization of steroidogenic enzymes (P450scc, P450c17, 3betaHSD and P450arom), spermatogenesis and cell proliferation were analyzed in the testes of fetal (164 to 218 days of fetal age), fawn (0 years old), yearling (1 year old) and adult (more than 2 years old) male sika deer. Three kinds of steroidogenic enzymes, P450scc, P450c17 and 3betaHSD, essential for the synthesis of testosterone were located only in the Leydig cells of the testes from the fetal period, and these localizations did not change during developmental or seasonal stages. Immunoreactivity for P450arom, a key enzyme converting testosterone to estradiol, was also localized only in the Leydig cells of testes but was also further limited to the testes of yearlings and adults. Seminiferous tubules had already formed in the fetal testes examined in the present study. Spermatogenesis started in yearlings and was more active in the breeding season. In the adult sika deer testes, the Leydig cells, which disp...Continue Reading

References

Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Jul 1, 1994·Domestic Animal Endocrinology·K M EisenhauerJ F Roser
Feb 1, 1997·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·G A BubenikL Bartos
Jan 1, 1997·Reproduction, Fertility, and Development·B BilińskaB Schmalz
Jun 23, 2001·Biology of Reproduction·L D QuirkeK P McNatty
Nov 8, 2001·Proceedings of the National Academy of Sciences of the United States of America·Q ZhouR A Hess
Mar 1, 1957·The American Journal of Anatomy·Y CLERMONT, B PEREY
Oct 21, 2003·World Journal of Urology·G R DohleR F A Weber
Nov 6, 2003·The Journal of Veterinary Medical Science·Weng QiangToshio Tsubota
Dec 9, 2004·The Journal of Veterinary Medical Science·Daisuke HayakawaJunzo Yamada
Jun 10, 2005·Reproduction in Domestic Animals = Zuchthygiene·H M MutembeiB Hoffmann
Sep 29, 2005·Reproductive Biology and Endocrinology : RB&E·Benson T Akingbemi
Sep 30, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Géraldine DelbèsRené Habert
Jan 25, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Susanne HaeusslerRolf Claus

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Citations

Feb 10, 2012·Spermatogenesis·Jenna T HaverfieldSarah J Meachem
Nov 29, 2016·The Journal of Reproduction and Development·Junko Noguchi
Jul 26, 2019·The Journal of Veterinary Medical Science·Anni NurlianiNobuo Kitamura
Jan 1, 2013·Basic and Clinical Andrology·Caroline BordayRené Habert

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