Immunohistochemical profile of odontogenic epithelium in developing dog teeth (Canis familiaris)

Veterinary Pathology
S NelS C Boy

Abstract

Tumors of the jaw bones and oral soft tissue are relatively common lesions in dogs. The aim of this study was to find cell markers to differentiate odontogenic epithelium from nonodontogenic epithelium for future research on the pathogenesis and pathology of odontogenic neoplasms in dogs. Keratin 14 and 19 staining was observed in odontogenic and nonodontogenic epithelium, whereas amelogenin and p75 neurotrophin receptor immunoreactivity was observed in certain odontogenic epithelial cells at various stages of development but not in other epithelial cells. Calretinin staining was observed in the alveolar epithelial cells directly overlying the developing tooth germ in 28 of 39 sections (71.8%), as well as the dental laminae in 30 of 35 sections (85.7%) and Serres rests in 24 of 28 sections (85.7%). Focal positivity was detected in the respiratory mucosa, some hair follicles, and fusion epithelium of the palate, but no calretinin staining was observed in other oral epithelial cells; therefore, calretinin has potential to be utilized as a marker to differentiate odontogenic form nonodontogenic epithelium.

References

Dec 1, 1986·Journal of Periodontology·D L Massoth, B A Dale
May 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·K HeikinheimoR P Happonen
Jun 1, 1987·Oral Surgery, Oral Medicine, and Oral Pathology·A Buchner, J J Sciubba
Jun 1, 1995·European Journal of Biochemistry·B SchwallerW Hunziker
Jan 1, 1994·Annual Review of Biochemistry·E Fuchs, K Weber
Feb 1, 1993·Cell and Tissue Research·C AndressenM R Celio
Jan 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·T WurtzL Hammarström
Jan 1, 1996·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·D G Gardner
Dec 30, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Y LuH Nikai
Aug 12, 1999·Journal of Structural Biology·A G FinchamJ P Simmer
Jan 5, 2000·Journal of Cellular Biochemistry·P PapagerakisA Berdal
Mar 8, 2000·European Journal of Oral Sciences·M G DominguesN S Araújo
May 12, 2001·European Journal of Oral Sciences·J C HuJ P Simmer
Sep 22, 2001·Matrix Biology : Journal of the International Society for Matrix Biology·J Moradian-Oldak
Jan 17, 2002·Medical Electron Microscopy : Official Journal of the Clinical Electron Microscopy Society of Japan·Y AbikoT Kaku
Aug 10, 2002·Progress in Neurobiology·Philippe P Roux, Philip A Barker
Mar 6, 2003·Oral Diseases·M M CriveliniN S de Araújo
Apr 2, 2003·Bone·P PapagerakisA Berdal
Mar 16, 2004·Veterinary Pathology·H UekiH Yoshikawa
Oct 9, 2004·The Journal of Veterinary Medical Science·Kazuhiro WatanabeToru Fujinaga
May 11, 2005·Journal of Oral Science·María Angélica Torres-QuintanaNelson Lobos
Jun 17, 2005·Archives of Oral Biology·P K DenBestenW Li
Jun 17, 2005·Archives of Oral Biology·Takahiko MorotomiHidemitsu Harada
May 6, 2006·European Journal of Oral Sciences·Qiaomei YanPamela K DenBesten
Aug 26, 2006·Journal of Dental Research·L YeP K Den Besten
Mar 30, 2007·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Amir HazeDan Deutsch

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Citations

Nov 21, 2014·Head and Neck Pathology·Keith D Hunter, Paul M Speight
Dec 22, 2017·Veterinary Pathology·Tuddow ThaiwongMatti Kiupel
Nov 28, 2013·Journal of Vascular Research·Ines Drenjancevic, Aleksandar Kibel
May 17, 2017·Veterinary Clinical Pathology·Ronaldo V Leite-FilhoSaulo P Pavarini
Jan 17, 2020·Journal of Oral and Maxillofacial Pathology : JOMFP·Amrutha RudrarajuK Roja Lakshmi
Aug 12, 2016·Veterinary Pathology·K HirayamaH Taniyama

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