Immunolabeling indicates that sulfhydryl oxidase is absent in anamniote epidermis but marks the process of cornification in the skin of terrestrial vertebrates.

Journal of Morphology
L Alibardi

Abstract

The passage between keratinization to cornification of the epidermis and skin appendages in vertebrates requires formation of a stratum corneum rich in SS bonds among other cross-linking chemical bonds. A key enzyme, sulfhydryl oxidase (SOXase) catalyzes the oxidation of SH groups present in keratins and in corneous proteins of the epidermis into SS. Presence and distribution of SAXase has been studied by immunohistochemistry in all vertebrates, from fish to mammals. SOXase is immunohistochemically absent in all fish and amphibian species tested with the exception of a thin pre-corneous layer in the epidermis of adult anurans. SOXase is low to absent in corneous appendages such as horny teeth of lamprey or claws and horny beaks of amphibians. Conversely, SOXase is detected in the transitional (pre-corneous) and inner corneous layers of the epidermis of sauropsids and mammals. In lepidosaurian reptiles, SOXase appears in both beta- and alpha-corneous-layers, but is limited to the pre-corneous and corneous layers of the thin soft epidermises of birds and mammals, including the granular layer. SOXase is localized in pre-corneous layers and disappears in external corneous layers of amniote skin appendages such as claws, beak...Continue Reading

References

Jan 1, 1987·Archives of Dermatological Research·H YamadaH Ogawa
Feb 1, 1966·Biological Reviews of the Cambridge Philosophical Society·R I Spearman
Oct 1, 1980·Biochimica Et Biophysica Acta·K TakamoriL A Goldsmith
Jun 1, 1993·The Journal of Investigative Dermatology·P M Steinert
Jan 2, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·R B Presland, B A Dale
Sep 5, 2002·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Andrey E KalininPeter M Steinert
Dec 4, 2002·Advanced Drug Delivery Reviews·Gopinathan K Menon
Sep 2, 2003·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Vladimir A Botchkarev, Ralf Paus
Jul 24, 2004·The International Journal of Developmental Biology·George E Rogers
Mar 31, 2005·International Review of Cytology·Lutz Langbein, Jürgen Schweizer
Apr 2, 2005·Nature Reviews. Molecular Cell Biology·Eleonora CandiGerry Melino
Sep 15, 2005·Cell and Tissue Research·Anna TuryDominique Fellmann
Sep 24, 2005·Experimental Dermatology·Peter M Elias, Eung Ho Choi
Nov 24, 2007·Journal of Molecular Histology·Kelly F PortesLia S Nakao
Nov 3, 2011·Molecular Biology and Evolution·Wim Vandebergh, Franky Bossuyt
Jun 25, 2013·Biochimica Et Biophysica Acta·Leopold EckhartWim Declercq
Mar 31, 2015·International Immunology·Takeshi Matsui, Masayuki Amagai
May 8, 2015·BMC Evolutionary Biology·Bettina StrasserLeopold Eckhart
Jan 15, 2019·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Karin Brigit HolthausLorenzo Alibardi
Dec 12, 2019·Molecular Biology and Evolution·Florian EhrlichLeopold Eckhart

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.