PMID: 6966345Mar 1, 1980Paper

Immunological approaches to cancer treatment

The Japanese Journal of Surgery
R W Baldwin

Abstract

Immunological approaches to cancer treatment are reviewed to consider the role of specifically sensitized effector cells as well as non-specific mechanisms. The induction of immunity by specific mechanisms is exemplified by the response to carcinogen induced animal tumours but this is contrasted with the lack of this type of response with naturally occurring animal tumours. These experimental findings are reviewed in relation to the clinical approaches to active immunotherapy. Regional immunotherapy, where bacterial adjuvants are administered so as to localize in tumour deposits is generally more effective than systemic immunotherapy. This is discussed in relation to the animal studies and these approaches are reviewed, particularly in connection with the treatment of human lung cancer.

References

Feb 21, 1976·Lancet·M F McKneallyH W Kausel
May 7, 1977·Lancet·M F McKneallyH W Kausel
Dec 23, 1977·Biochimica Et Biophysica Acta·K E HellströmJ T Nepom
Jan 1, 1977·Contemporary Topics in Molecular Immunology·R W Baldwin, R A Robins
Feb 26, 1977·British Medical Journal·M B McIllmurrayM Deane
Jan 1, 1978·Advances in Cancer Research·L Milas, M T Scott
Jan 1, 1978·Annual Review of Medicine·J E Goodnight, D L Morton
Jul 1, 1978·Journal of the National Cancer Institute·S BroderT A Waldmann
Jan 1, 1978·Advances in Cancer Research·R B Herberman, H T Holden
Jan 1, 1978·Advances in Cancer Research·R W Baldwin, M V Pimm
Sep 15, 1979·International Journal of Cancer. Journal International Du Cancer·N WillmottR W Baldwin
Feb 15, 1978·International Journal of Cancer. Journal International Du Cancer·J R OehlerR B Herberman
Jan 1, 1978·Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer·P B IlesR W Baldwin
Jan 1, 1974·Advances in Immunology·J C Cerottini, K T Brunner
Jan 1, 1974·Advances in Cancer Research·R B Herberman
Sep 15, 1973·International Journal of Cancer. Journal International Du Cancer·R W Baldwin, M V Pimm
Jan 5, 1980·Lancet·J LoweR W Baldwin

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Citations

Oct 1, 1981·The Australian and New Zealand Journal of Surgery·A K House
Apr 10, 2010·The Behavioral and Brain Sciences·David A Coall, Ralph Hertwig

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