PMID: 7018419Jul 1, 1980Paper

Immunological disorders in a patient with Whitaker syndrome (author's transl)

Annali Sclavo; rivista di microbiologia e di immunologia
C Adami LamiA Vierucci

Abstract

Some immunological parameters have been examinated in a 13-year-old girl with Whitaker syndrome and in her closest blood-relatives. Absolute and percentage values of T and B lyphocytes were normal, whereas mitogen responsiveness was over normal range before therapy had begun. This phenomen did not appear if the cultures were carried out in presence of autologous serum. Neutrophil function was defective in responsiveness to chemotactic stimulation, but NBT reduction as well as bactericidal activity were normal. Defects both in mitogen responsiveness and chemotaxis have been pointed out in the parents and in the patient's twin brother. The immunologic disorders observed are discussed in the light of the clinical and functional pecularities of Whitaker's syndrome.

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Addison Disease

Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones. Discover the latest research on Addison's disease here.