Immunological impairment of pregnancy in mice by lactate dehydrogenase-X

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Immunological impairment of pregnancy in mice by lactate dehydrogenase-X

Abstract

Citations

Expression of recombinant mouse sperm protein sp56 and assessment of its potential for use as an antigen in an immunocontraceptive vaccine

Binding of antibody to LDH-X by the mouse blastocyst. 1

A logical approach to the isolation of lactate dehydrogenase isozyme X from human testes: a general rationale for the isolation of homotetrameric LDH isozymes

Effects on fertility of immunization against lactate dehydrogenase X in female mice.

Immunohistochemical localization of LDH-x during spermatogenesis in mouse testes.

Detection of sperm antigens on mouse ova and early embryos

Binding of lactate dehydrogenase isozyme X (LDH-X) by sperm antibodies of infertile humans

Identification of an antigenic determinant of mouse lactate dehydrogenase C4

The antigenicity of synthetic peptide fragments of lactate dehydrogenase C4

Antigenic domains of the sperm-specific lactate dehydrogenase C4 isozyme

Immunogenicity of peptides having pre-determined alpha-helical and alpha-alpha fold topologies

Resistance of female guinea pig fertility to efficient iso-immunization with spermatozoa autoantigens

Immunobiological consequence of immunization of female mice with homologous spermatozoa: induction of infertility

Inhibitory effects of monoclonal sperm antibodies on the fertilization of mouse oocytes in vitro and in vivo

Selective inhibition of the sperm-specific lactate dehydrogenase isozyme-C4 by N-isopropyl oxamate

The antigenic and immunogenic properties of synthetic peptide immunocontraceptive vaccine candidates based on gamete antigens

Characterization of monoclonal antibodies to the sperm-specific lactate dehydrogenase isozyme

Immunization of male but not female mice with the sperm-specific isozyme of lactate dehydrogenase (LDH-C4) impairs fertilization in vivo

Sperm proteins being studied for use in a contraceptive vaccine

Update on the Center for Recombinant Gamete Contraceptive Vaccinogens

Rapid purification of lactate dehydrogenase X from mouse testes by two steps of affinity chromatography on oxamate-sepharose.

The effects of antibody sperm-egg interaction

Immunochemical dissection of the testes-specific isozyme lactate dehydrogenase C4

Subcellular distribution of the lactate dehydrogenase isozyme specific for testis and sperm.

Cloning, sequencing, and characterization of LDH-C4 from a fox testis cDNA library

Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20

Anti-acrosin antibodies in sera, colostrum and genital organs of vaccinated ewes: estimation and correlation with fertility.

Correlation of antispermatozoal antibody with infertility in immunized female rabbits using 14C-protein A in a filter radioassay

The fertilization antigen (FA-1): applications in immunocontraception and infertility in humans

Lactate dehydrogenase X: effects of antibody on mouse gametes but not on early development.

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Infertility in female rabbits immunized with lactate dehydrogenase X

Identification of an antigenic determinant of mouse lactate dehydrogenase C4

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Lactate dehydrogenase X: effects of antibody on mouse gametes but not on early development.