PMID: 6966676Jun 1, 1980Paper

Immunological indices in presenile Alzheimer's disease

Journal of the Neurological Sciences
B Tavolato, V Argentiero

Abstract

Immunological indices, both T- and B-dependent, were studied in 11 patients affected by presenile Alzheimer's disease. The data obtained were compared with those from a group of normal adults of similar age and from a group of normal young subjects. Furthermore, antisera were produced in rabbits against Alzheimer's serum and compared to antisera against normal human serum. The following results were obtained: decrease of serum IgM levels; no monoclonal aspects or auto-antibodies were detected in our patients. The kappa/lambda ratio was also normal. The T cell system was functionally normaly, but with a slight decrease of the T cell number and with an increase of the Null lymphocytes. No specific serum proteins were found in the anti-Alzheimer antisera. The data are discussed in correlation to the possible genesis of senile plaques.

References

Jan 1, 1977·Scandinavian Journal of Immunology·P M JohnsonE Linder
Sep 1, 1975·Journal of the Neurological Sciences·A B TodorovR C Elston
Dec 12, 1975·Science·H M WiśniewskiH Fraser
Mar 1, 1976·Cellular Immunology·M H Claësson
Oct 19, 1974·Lancet·S Gupta, M H Grieco
May 17, 1973·The New England Journal of Medicine·J Wybran, H H Fudenberg

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Citations

Jan 1, 1990·Journal of Clinical Laboratory Analysis·A OunanianS Avrameas
Aug 1, 1994·Molecular Neurobiology·V K Singh
Jan 1, 1989·Journal of Psychiatric Research·G D TollefsonM Garvey
Jul 1, 1992·Journal of Psychiatric Research·M W DyskenT Sunderland
Jan 1, 1986·Mechanisms of Ageing and Development·V K SinghF R Brown
Jan 1, 1987·Neurobiology of Aging·A D KayS I Rapoport
Feb 1, 1985·Journal of Neuroimmunology·N KhansariH H Fudenberg
Mar 1, 2003·Expert Review of Neurotherapeutics·Amanda McRae, Eng Ang Ling
Mar 1, 1993·Journal of the American Geriatrics Society·R B Scott
Oct 1, 1985·Journal of the American Geriatrics Society·O J ThienhausH B Bosmann
Aug 1, 1989·Journal of the American Geriatrics Society·A AdunskyM Rabinowitz
Oct 20, 1998·The International Journal of Neuroscience·M PopovićN Popović
May 1, 1982·Acta Psychiatrica Scandinavica·B PentlandP L Yap
Feb 1, 1997·The International Journal of Neuroscience·M PopovićL Rakić
Nov 12, 2009·Expert Review of Neurotherapeutics·Kavon Rezai-ZadehTerrence Town
Jan 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·C JonkerP Tavenier
Nov 1, 1989·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·D Gautrin, S Gauthier
Jan 1, 1991·Annals of the New York Academy of Sciences·M ShinitzkyA Elizur
Sep 1, 1984·Drug Intelligence & Clinical Pharmacy·K L Rathmann, C S Conner
Aug 1, 1985·Journal of the Neurological Sciences·I ElovaaraT Erkinjuntti

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