PMID: 8967534Jan 1, 1996Paper

Immunological studies of the peripheral blood in endometriosis patients

Akusherstvo i ginekologii︠a︡
D Genov, R Rusev

Abstract

The present facts on immunity system in women with endometriosis are quite contradictory. We investigated 30 women with hystological proven diagnosis, divided into three groups: 1st group-10 women with myoma uteri, 2nd group-10 women with endometriosis, 3rd group-10 women with adnexitis chronica. Control group were 65 healthy women in reproductive age between 24-42 years. It is established, that in the 3 groups cell immunity is oppressed, but more highly expressed in women with endometriosis (Tact and Ttot. p < 0.001). There are not changes in the levels of B lymphocytes, but in the women with endometriosis they are most low. In the 3 groups NBT (Nitro Blue Tetrazolium) is with high values, i. e. there is increased dynamic activity on the neutrophils. The humoral immunity (lg G, lg A, lg M) are within the borders of standard. The results suggest the concept for disturbance of cells immunity in endometriosis.

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