Immunological therapeutics in acute aortic syndrome

Asian Cardiovascular & Thoracic Annals
Lara Jane RimmerMohamad Bashir

Abstract

Acute aortic syndrome is a group of interlinked conditions with common presenting symptoms, including aortic dissection, penetrating atherosclerotic ulcer, and intramural hematoma. Pharmacological management of acute aortic syndrome is a growing area, with key themes to address the underlying inflammatory pathways believed to be the cause. Research into interleukins, matrix metalloproteinases, and granulocyte macrophage colony-stimulating factor are just some of the many immunological properties being investigated and translated into medical therapies. Stem cell experiments may indicate further advances in the pathologies of acute aortic syndrome. The study of pharmacogenomics to improve treatment across different genomes is also a novel area outlined in this paper.

References

Mar 17, 2001·Heart·I Vilacosta, J A San Román
Feb 25, 2003·Nature Genetics·Enid R NeptuneHarry C Dietz
May 9, 2006·Postgraduate Medical Journal·F AhmadM Hamady
May 30, 2009·Vascular·Xiaoming ZhangScott A LeMaire
Dec 1, 2010·The Journal of Thoracic and Cardiovascular Surgery·Steven L LansmanDavid Spielvogel
Feb 26, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Lei ZhangZai-ping Jing
Aug 6, 2011·Journal of the American College of Cardiology·Toru SuzukiKim Eagle
Mar 24, 2012·The Annals of Thoracic Surgery·Ying H ShenScott A LeMaire
Nov 9, 2012·Circulation·Tomohiro KuriharaYasunori Okada
Apr 9, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Daniel Ricklin, John D Lambris
Sep 5, 2013·Circulation·Azeem S SheikhSajjad Mazhar
Oct 18, 2013·International Journal of Molecular Sciences·Nader MakkiFrancis J Miller
Jul 30, 2014·World Journal of Stem Cells·Aika Yamawaki-OgataYuji Narita
Jan 24, 2015·Circulation. Cardiovascular Genetics·Romy FrankenGerard Pals
Dec 15, 2015·Frontiers in Cardiovascular Medicine·Aleksandra Piechota-PolanczykChristine Brostjan
Apr 14, 2016·Aorta : Official Journal of the Aortic Institute at Yale-New Haven Hospital·Hisham M F Sherif
Jun 6, 2016·Journal of Pharmacological Sciences·Seiji UenoHiroyuki Sakurai
Jul 8, 2016·Annals of Cardiothoracic Surgery·Joel S Corvera
Aug 18, 2016·JAMA : the Journal of the American Medical Association·Firas F MussaKim A Eagle
Aug 29, 2017·The New England Journal of Medicine·Paul M RidkerUNKNOWN CANTOS Trial Group
Oct 11, 2017·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Robert J Hinchliffe
Oct 28, 2017·Journal of the American College of Cardiology·Peter Libby
Nov 7, 2017·European Heart Journal·Eduardo BossoneKim A Eagle
Nov 11, 2017·Molecular Oncology·Sara SigismundLetizia Lanzetti
Jul 25, 2018·Progress in Cardiovascular Diseases·Erica RuraliGiulio Pompilio
Jan 18, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Dianna M Milewicz, Francesco Ramirez
Aug 9, 2019·Pharmaceuticals·Eithne M MaguireQingzhong Xiao
Aug 31, 2019·Journal of Immunology Research·Noemi CifaniFlavia Del Porto

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