Immunologically demonstrable hormones and hormone-like molecules in rat white blood cells and mast cells

Cell Biology International
György CsabaEva Pállinger

Abstract

The presence or absence of four biologically active hormone or hormone-like molecules was studied in rat immune cells using specific antibodies with flow cytometry and confocal microscopy. Epidermal growth factor (EGF) was not demonstrable at all, digoxin was present only in blood lymphocytes, and insulin was found in the monocyte-macrophage-granulocyte group in peritoneal fluid and thymic lymphocytes. Immunologically demonstrable triiodothyronine (T3) was present in all cells studied (lymphocytes, mast cells and monocyte-macrophage-granulocytes in peritoneal fluid and blood, and thymic lymphocytes). While there is no explanation of the presence of digoxin and insulin, it is assumed that T3 is an extrathyroidal source of the hormone that is needed for maintaining cell proliferation and normal status in the immune system, particularly as it is absent in the case of transitional or durable thyroid deficiency.

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Apr 6, 2007·Cell Biology International·G CsabaEva Pállinger

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Citations

Oct 23, 2013·Brain, Behavior, and Immunity·Tyler J StevensonBrian J Prendergast
Apr 15, 2006·Cell Biochemistry and Function·Eva Pállinger, G Csaba
Nov 14, 2006·Cell Biochemistry and Function·György CsabaEva Pállinger
Mar 25, 2014·Fish & Shellfish Immunology·A Quesada-GarcíaJ M Navas
Feb 18, 2015·European Journal of Immunology·Anuska M Alvares-SaraivaMario Mariano
Sep 30, 2014·Acta Microbiologica Et Immunologica Hungarica·György Csaba
Dec 3, 2013·Acta Microbiologica Et Immunologica Hungarica·Eva PállingerGyörgy Csaba
Dec 17, 2014·Acta Microbiologica Et Immunologica Hungarica·Éva Pállinger, György Csaba
Jun 19, 2014·Acta Microbiologica Et Immunologica Hungarica·György Csaba
Mar 7, 2009·Acta Physiologica Hungarica·Gy Csaba, E Pállinger
Apr 1, 2011·Acta Microbiologica Et Immunologica Hungarica·Eva PállingerG Csaba
Jul 12, 2005·Acta Physiologica Hungarica·Elva Pállinger, G Csaba
Mar 9, 2017·International Reviews of Immunology·María Cecilia OpazoClaudia A Riedel

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