PMID: 6405344Feb 1, 1983Paper

Immunology of the inner ear: response of the inner ear to antigen challenge

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
J P Harris

Abstract

The relationship of the inner ear to host immunity and the immunoresponsiveness of the inner ear to antigen challenge were investigated. A radioimmunoassay was used to quantitate antibody titers to keyhole-limpet hemocyanin generated in the serum, perilymph, and CSF of guinea pigs following systemic or inner ear immunizations. The results of these experiments demonstrate (1) the blood-labyrinth barrier is analogous to the blood-brain barrier with respect to immunoglobulin equilibrium, (2) the inner ear is capable of responding to antigen challenge, and (3) the inner ear is an effective route for systemic immunization.

References

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Citations

Dec 1, 1992·The Annals of Otology, Rhinology, and Laryngology·S Yamanobe, J P Harris
May 1, 1984·Acta Oto-laryngologica·N RasmussenM Tos
Sep 1, 1996·The Journal of Laryngology and Otology·A A Parikh, G B Brookes
Jul 13, 1999·The Laryngoscope·F OttavianiR Manna
May 12, 2000·Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao·S GongJ Wang
Mar 16, 2000·The Laryngoscope·C MaE M Keithley
Feb 15, 2001·Current Opinion in Neurology·A F RyanJ P Harris
Sep 5, 2002·Acta Oto-laryngologica. Supplementum·Allen F RyanElizabeth M Keithley
Nov 8, 2007·Current Allergy and Asthma Reports·M Jennifer Derebery, Karen I Berliner
Nov 4, 2009·Immunotherapy·Maria C BunielVincent K Tuohy
Feb 26, 2013·Rheumatology·Tamara MijovicInés Colmegna
Sep 8, 2017·Frontiers in Cellular Neuroscience·Shimon P Francis, Lisa L Cunningham
Jul 1, 1989·Acta Oto-laryngologica·B Gloddek, J P Harris
May 1, 1987·The Annals of Otology, Rhinology, and Laryngology·Y OhashiM Kato
Nov 1, 1986·Acta Oto-laryngologica·N K Woolf, J P Harris
Dec 10, 1999·Acta Oto-laryngologica·S TomiyamaT Yagi
Aug 23, 2006·Acta Oto-laryngologica·R BovoA Martini
Sep 21, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·Michael J Ruckenstein
Aug 13, 2011·Endocrine·Dilek BerkerSerdar Guler
Nov 22, 2011·The Annals of Otology, Rhinology, and Laryngology·Jeremy HornibrookJohn Gourley
Mar 5, 2019·Laryngoscope Investigative Otolaryngology·Hitomi Sakano, Jeffrey P Harris
Jan 12, 2019·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Rahul MittalAdrien A Eshraghi
Apr 13, 2020·Dermatologic Therapy·Goksen ErtugrulEmre Soylemez
Mar 21, 2020·Frontiers in Neurology·Hiroshi NakanishiAndrew J Griffith
Jan 1, 1987·Archives of Oto-rhino-laryngology·H YamaneK Takahashi
Mar 1, 1985·The Annals of Otology, Rhinology, and Laryngology·J P Harris, A F Ryan
Mar 1, 1984·The Annals of Otology, Rhinology, and Laryngology·J P Harris
Jan 10, 1998·The Annals of Otology, Rhinology, and Laryngology·T Takasu, J P Harris
Jun 9, 1998·Annals of the New York Academy of Sciences·R FilipoG Nostro
Jan 1, 1989·Acta Oto-laryngologica. Supplementum·G MogiH Kawauchi
Jan 1, 1995·The Journal of Laryngology and Otology·M Y CaoJ P Tomasi
Mar 9, 2004·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A BaumannD Vibert
May 24, 1995·Molecular and Cellular Biochemistry·M Y CaoJ P Tomasi
Jan 27, 2000·Current Opinion in Rheumatology·J H Stone, H W Francis
Jan 25, 2003·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Xiaobo WangElizabeth M Keithley
Jul 29, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Mehdi BakhshaeeMohammadtaghi Shakeri
Apr 8, 2015·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·A F Goodall, M A Siddiq
Mar 10, 2018·The Laryngoscope·Anita JeyakumarBrian J McKinnon

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