Immunomodulating and anti-tumor action of extracts of several mushrooms

Journal of Biotechnology
Mark ShamtsyanNina Denisova

Abstract

Aqueous extracts from fruit bodies and mycelia of various higher Basidiomycetes were studied in search for reliable biological effects. In vitro and in vivo experiments were conducted. The results showed that the aqueous extracts demonstrated various types of marked biological actions: an increased production of reactive oxygen forms by neutrophil cells of human peripheral blood; a significant mitogenic activity in a wide range of concentrations; stimulation on production of inflammatory cytokines interleukine 1-beta and interleukine-8 by peripheral blood cells; a decrease in both average tumor size in mice with transplanted melanoma B16 and a manifestation of tumorous intoxication; and a prolongation in the survival rate of such mice.

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Citations

Jan 15, 2009·Evidence-based Complementary and Alternative Medicine : ECAM·Miki FukudaMinoru Takeuchi
Jul 21, 2009·Chemico-biological Interactions·Fei-yan LiuTim-tak Kwok
Jul 22, 2008·Journal of Ethnopharmacology·Sun Kyung KimSeung Hyun Han
Sep 1, 2008·Environmental Toxicology and Pharmacology·Swatilekha MaitiTapas K Maiti
Dec 17, 2009·Letters in Applied Microbiology·M-Y Lung, P-C Huang
Jul 29, 2016·World Journal of Microbiology & Biotechnology·Małgorzata PleszczyńskaJanusz Szczodrak
Jun 20, 2006·International Immunopharmacology·Itisam SarangiTapas K Maiti
Aug 7, 2012·Food & Function·Lu RenYacine Hemar
Apr 6, 2017·World Journal of Microbiology & Biotechnology·Małgorzata PleszczyńskaJanusz Szczodrak
Oct 15, 2018·Molecular Biology Reports·Katarzyna Sułkowska-ZiajaBożena Muszyńska
Nov 1, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Boris JakopovicSandra Kraljević Pavelić
May 6, 2021·Journal of Fungi·Jelena ŽivkovićJasmina Glamočlija
Jul 20, 2021·International Journal of Biological Macromolecules·Xiomara López-LegardaFreimar Segura-Sánchez

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