Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina

Fitoterapia
Jiong-Ran ChenMeng Wang

Abstract

The polysaccharide (PAP) from Potentilla anserina was evaluated for modulating effects by using mouse peritoneal macrophage and the immunosuppressed-model cyclophosphamide-induced. Phagocytotic and mononuclear phagocytic system function assays showed that PAP stimulated the phagocytosis of phagocyte. Splenocyte proliferation assay showed that PAP acted the effect combining Con A or LPS in splenocyte proliferation. The parameters detected showed that PAP increased thymus and spleen indices, the levels of LDH and ACP in the spleen, and IL-10 and IFN-γ in serum in immunosuppressed mice. The results suggest that PAP is involved in immunomodulatory effects leading to the exploration for PAP as a potential immunostimulant.

References

Jan 1, 1992·Advances in Experimental Medicine and Biology·R J NoelleH P Fell
Jan 1, 1989·Advances in Immunology·T R Mosmann, R L Coffman
Oct 31, 1996·Nature·A K AbbasA Sher
Aug 7, 1999·Immunopharmacology·Y J JeonH M Kim
Apr 4, 2001·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·R W BirkS Goerdt
Nov 5, 2002·Critical Reviews in Oncology/hematology·A H KlimpT Daemen
Dec 19, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·C BodinetJ Freudenstein
Oct 27, 2004·Immunology·Lynn M WilliamsBrian M J Foxwell
Nov 9, 2005·International Immunopharmacology·Igor A SchepetkinMark T Quinn
Jan 24, 2006·International Immunopharmacology·Igor A Schepetkin, Mark T Quinn
Dec 11, 2007·International Immunopharmacology·Anwei ChengXueming Xu
Mar 14, 2008·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Y-L ZhaoX-H Xiao
Jul 8, 2008·International Journal of Biological Macromolecules·Xiaoming ChenLiqin Jin
Jun 30, 2009·International Journal of Biological Macromolecules·Ting-Jun HuRong-Liang Zheng
Oct 16, 2009·International Journal of Biological Macromolecules·Yali ZhangJianbao Zhang

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Citations

Oct 2, 2013·International Journal of Biological Macromolecules·Yu-xia MeiYun-xiang Liang
Dec 20, 2012·International Journal of Environmental Research and Public Health·Zi-Luan FanShuang-Qi Tian
Oct 16, 2014·Journal of Agricultural and Food Chemistry·Zhuqing DaiXiaoxiong Zeng
Dec 4, 2013·International Journal of Biological Macromolecules·Jianteng WeiDuolong Di
Apr 5, 2014·Phytochemistry·Toshio MorikawaOsamu Muraoka
Aug 8, 2014·International Journal of Biological Macromolecules·Zhe RenHaibin Zhang
Sep 2, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yuan-Yuan DengMing-Wei Zhang
Nov 26, 2015·BMC Complementary and Alternative Medicine·Sihui MaMeiyu Xu
Jan 5, 2012·International Journal of Biological Macromolecules·Ying-Yi WeiShu-Xia Zhang
Sep 18, 2012·Journal of Ethnopharmacology·Xi LiYanjun Yang
Jan 15, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Enhui CuiXiaoping Song
Jul 2, 2016·International Journal of Biological Macromolecules·Faizan Naeem RazaliAdawiyah Suriza Shuib
Dec 14, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yang YiZhen-Cheng Wei
Oct 12, 2017·Journal of Natural Medicines·Toshio MorikawaKiyofumi Ninomiya
Mar 31, 2019·Chembiochem : a European Journal of Chemical Biology·Yuping ShenJames P Tam
Jun 2, 2020·Biological & Pharmaceutical Bulletin·Zhangbao ChenHui Li
Jul 10, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Klaudia KowalikMichał Tomczyk
Nov 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sulhee LeeYoung-Seo Park
Apr 21, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Hsiao-Chien Lin, Jin-Yuarn Lin
Oct 20, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qiuchen QiZhongxi Zhao
Jun 26, 2020·Frontiers in Bioengineering and Biotechnology·Guangyu ChuLiang Liu
Jul 11, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Jipeng ShiJi Zhang

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