PMID: 11923111Mar 30, 2002Paper

Immunoneutralization and anti-idiotype production: two-sided applications of leptin

Trends in Immunology
Brant A De FantiJ A Martínez

Abstract

The neuroendocrine and immune systems are linked through a complex bi-directional network, in which hormones modify immune function, and the immune system, through the action of cytokines, affects neuroendocrine responses involved in the maintenance of body homeostasis. The adipocyte-derived, peptide hormone leptin is a pleiotropic molecule belonging to the helical cytokine family. On pp. 182-187, Matarese et al. suggest the possibility of new leptin-based therapeutic strategies for the treatment of both infection and autoimmune disease.

References

May 1, 1996·Nature Genetics·M S PhillipsJ F Hess

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Citations

Oct 14, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Fuat GurkanNuriye Mete
Dec 17, 2014·Metabolism: Clinical and Experimental·Neira SáinzJosé Alfredo Martínez
Jun 16, 2017·Nature Reviews. Disease Primers·Pedro González-MuniesaJ Alfredo Martinez
Jan 22, 2019·Current Protein & Peptide Science·Eglantina IdrizajMaria Caterina Baccari

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